Example sentences for: alkaloids

How can you use “alkaloids” in a sentence? Here are some example sentences to help you improve your vocabulary:

  • utilis) that produce a dose-related increase in the clotting time of blood induced by carpet viper venom ( Echis carinatus ) would be useful against bites from Bothrops species that cause haemorrhage at the point of injection due to the inhibition of the clotting mechanism [ 40 ] . Antivenom compounds so far isolated from plants include protocatechuic acid, a catechin-gallo-catechin tannin, caffeic acid derivatives (chlorogenic acid, cynarin), coumarins (bergapten), flavonoids (rutin, isoscutellarein, kaempferol, quercetin, hesperidin), ar-turmerone, alkaloids (aristolochic acid), triterpenoids, triterpenes, coumestans (wedelolactone), sterols (sitosterol, stigmasterol, beta-amyrin), triterpenoid glycosides, alkaloids (allantoin) and lignoflavonoids [ 43 40 44 42 ] . Many relevant compounds are widely distributed nitrogen-free, low molecular weight compounds (except aristolochic acid, an untypical non-basic, nitro-derivative) [ 38 ] . The structural similarities of certain plant chemicals found in plants used for snakebites are an isoflavone skeleton, acidic nature and dioxygenated functionality [ 44 ] .

  • The use of Justicia secunda for rashes has been previously recorded [ 52 ] . Different species have yielded steroids, lignans, betaine, triterpenoids, coumarins, dihydrocoumarin, umbelliferone and 3-(2-hydroxyphenyl) propionic acid alkaloids and flavonoids [ 90 91 92 ] . Coumarins and flavonoids have anti-inflammatory properties [ 38 11 ] . Wounds on Wistar rats treated with organic and aqueous extracts of Justicia pectoralis showed intermediate swelling in comparison to wounds treated with coumarin isolated from the plant extract (least swelling) and the controls [ 93 ] . This study supported local usage for wound-healing properties.

  • It was demonstrated that one group of antimitotic agents, vinca alkaloids, bind with similar affinity to all β-tubulin isotypes [ 12 ] , thus suggesting for therapy with vinorelbine, vinblas-tine, or vincristine that tubulin isotype levels are incidental for efficacy.

  • Stimulation of the immune system might also contribute to reducing the effects of snakebites and improvement in recovery from envemomization by contributing to a more rapid removal of the venom [ 11 ] . Chlorogenic acid acts as an antidote by binding to proteins through hydrophobic interactions and hydrogen bonds [ 41 ] . It presents anticomplementary action at the classical pathway [ 41 ] . Analgesic properties like those provided by tropane alkaloids would also lessen the pain of the bite, as would compounds that act as sedatives and tranquilisers [ 40 ] .

  • Aframomum melegueta has been previously recorded as a stimulant [ 50 ] . Caribs of Dominica used Aframomum granum-paradisi leaves on their bodies while they were bathing and the plant was also given to their hunting dogs [ 16 ] . Seeds were put into rum as a 'chauffe' to excite dogs [ 16 ] . Aframomum granum-paradisi contains alkaloids (piperine), essential oils and resins [ 54 ] .


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