Example sentences for: alkaloids

How can you use “alkaloids” in a sentence? Here are some example sentences to help you improve your vocabulary:

  • 4%) [ 128 ] . Some alkaloids are immunostimulants at very low doses [ 39 ] .

  • Scorpion venom when injected exerts a strong inflammatory response [ 11 ] . Many plant species used against stings contain compounds with antiinflammatory properties, flavonoids (rutin, hesperidin, quercetin), coumarins (bergapten), coumestans (wedelolactone), triterpenes, sterols and saponins [ 38 11 ] . The mechanism of action of the flavonoids is based on the inhibition of enzymatic steps in the arachidonic acid cascade [ 38 ] . Plant compounds that are immunostimulants at very low doses are some alkaloids, quinones, isobutylamides, phenolcarboxylic acid esters and terpenoids [ 39 ] . Other plant compounds with immunostimulatory effects are sesquiterpene lactones [ 40 ] . Many polysaccharides and glycoproteins enhance the unspecific immune system by activating the phagocytotic activity of granulocytes and macrophages, or by inducing cytokine production or influencing complement factors [ 39 ] .

  • The use of Justicia secunda for rashes has been previously recorded [ 52 ] . Different species have yielded steroids, lignans, betaine, triterpenoids, coumarins, dihydrocoumarin, umbelliferone and 3-(2-hydroxyphenyl) propionic acid alkaloids and flavonoids [ 90 91 92 ] . Coumarins and flavonoids have anti-inflammatory properties [ 38 11 ] . Wounds on Wistar rats treated with organic and aqueous extracts of Justicia pectoralis showed intermediate swelling in comparison to wounds treated with coumarin isolated from the plant extract (least swelling) and the controls [ 93 ] . This study supported local usage for wound-healing properties.

  • Because of the high catalytic efficiency and broad substrate specificity, β-lactamases have been extensively used in the ADEPT approach to activate prodrugs of vinca alkaloids [ 27 ] , nitrogen mustard [ 28 29 30 31 32 ] , doxorubicin [ 33 34 35 36 ] and others [ 37 ] . To take advantage of the potent antitumor activity of the CC-1065 class of compounds and the ADEPT approach, we have synthesized β-lactam prodrugs.

  • Stimulation of the immune system might also contribute to reducing the effects of snakebites and improvement in recovery from envemomization by contributing to a more rapid removal of the venom [ 11 ] . Chlorogenic acid acts as an antidote by binding to proteins through hydrophobic interactions and hydrogen bonds [ 41 ] . It presents anticomplementary action at the classical pathway [ 41 ] . Analgesic properties like those provided by tropane alkaloids would also lessen the pain of the bite, as would compounds that act as sedatives and tranquilisers [ 40 ] .


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