Example sentences for: aliphatic

How can you use “aliphatic” in a sentence? Here are some example sentences to help you improve your vocabulary:

  • They include: (1) sulfate esters of polysaccharides {carrageenan [ 1 16 17 18 19 ] , cellulose sulfate [ 12 13 14 15 ] , and dextran or dextrin sulfate [ 1 2 3 4 5 6 7 8 9 10 11 ] }; (2) aryl sulfonates {poly(naphthalene sulfonate) [ 22 23 24 ] and poly(styrene-4-sulfonate) [ 20 21 ] }; and (3) aliphatic {Carbomer 974P/BufferGel [ 25 26 27 28 29 ] } and aromatic carboxylates {CAP [ 30 31 32 33 34 35 36 37 ] }. The anti-HIV-1 properties of these polymers are expected to depend on their complexation with virus proteins which is likely to occur mainly through the formation of salt linkages or ion pairs between oppositely charged groups on the polymers and virus proteins, respectively [ 56 ] . However, the anti-HIV-1 properties of these polymers may depend not only on their charge density, but also on the characteristics of their uncharged portions, which may be involved in hydrophobic and hydrogen bonding interactions which can elicit profound conformational changes in hydrophobic regions of proteins and cause disassembly of complex proteins consisting of subunits [ 57 ] . For these reasons it is not be expected that all anionic polymers, considered as anti-HIV-1 microbicides, would have similar biological activities.

  • The report of the crystal structure of the homotetrameric ALDH1A1 enzyme from sheep liver revealed a substrate tunnel capable of binding retinal which was absent in ALDH2 and ALDH3A1 enzymes [ 9 ] . Likewise, the crystal structure reported for mouse ALDH1A2 revealed a substrate channel which could provide specificity for retinal and exclude short-chain aliphatic aldehydes [ 10 ] .

  • However, the data from this and other [ 22 29 ] studies suggest a clear preference for phenyl or aliphatic side chains (F, Y, L, I, V, M) in the +1 position.

  • Our results are in good agreement with the pair motifs that are formed with small residues, but do not favor pairs with β-branched aliphatic residues (isoleucine and valine).

  • The aliphatic portions of the side chains of both Lys61's may play roles in RNA binding since they cross the faces of both adenosines.


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