Words similar to aliphatic
Example sentences for: aliphatic
How can you use “aliphatic” in a sentence? Here are some example sentences to help you improve your vocabulary:
It is notable that the K61M substitution, which was designed to preserve the aliphatic characteristics of the lysine side chain while eliminating its amino group, causes a severe repressor defect in mutant homodimers.
This modification occurs on a cysteine residue, three residues proximal to the C-terminus with two aliphatic amino acids separating the cysteine from the C-terminus (hence the term CAAX box).
They include: (1) sulfate esters of polysaccharides {carrageenan [ 1 16 17 18 19 ] , cellulose sulfate [ 12 13 14 15 ] , and dextran or dextrin sulfate [ 1 2 3 4 5 6 7 8 9 10 11 ] }; (2) aryl sulfonates {poly(naphthalene sulfonate) [ 22 23 24 ] and poly(styrene-4-sulfonate) [ 20 21 ] }; and (3) aliphatic {Carbomer 974P/BufferGel [ 25 26 27 28 29 ] } and aromatic carboxylates {CAP [ 30 31 32 33 34 35 36 37 ] }. The anti-HIV-1 properties of these polymers are expected to depend on their complexation with virus proteins which is likely to occur mainly through the formation of salt linkages or ion pairs between oppositely charged groups on the polymers and virus proteins, respectively [ 56 ] . However, the anti-HIV-1 properties of these polymers may depend not only on their charge density, but also on the characteristics of their uncharged portions, which may be involved in hydrophobic and hydrogen bonding interactions which can elicit profound conformational changes in hydrophobic regions of proteins and cause disassembly of complex proteins consisting of subunits [ 57 ] . For these reasons it is not be expected that all anionic polymers, considered as anti-HIV-1 microbicides, would have similar biological activities.
Our results are in good agreement with the pair motifs that are formed with small residues, but do not favor pairs with β-branched aliphatic residues (isoleucine and valine).
We previously isolated a mutant, V29I, which increases the size of the side chain while retaining its aliphatic character.
Loading...