Example sentences for: agrp

How can you use “agrp” in a sentence? Here are some example sentences to help you improve your vocabulary:

  • These data suggest that in fasting and insulin-deficient diabetes, as in leptin-deficient ob/ob mice [ 9 19 ] , glucocorticoids dominate leptin and insulin levels in determining AGRP expression, whereas insulin and leptin dominate glucocorticoids in determining hypothalamic POMC expression.

  • As with AGRP mRNA, NPY mRNA was elevated in diabetic mice, and adrenalectomy blocked this induction of NPY mRNA in diabetic mice whether or not they were fasted (Fig.

  • Implantation of corticosterone implants for 48 hours significantly elevated hypothalamic AGRP expression compared to the placebo group (Fig.

  • On the other hand, blocking the rise in corticosterone by adrenalectomy prevented the reduction in hypothalamic POMC mRNA and the induction of AGRP mRNA, without reversing either the reduced leptin or the reduced adiposity, characteristic of insulin-deficient diabetic mice (Fig.

  • Five micrograms of total RNA from hypothalamus was subjected to Northern blot analysis, as described previously, to measure POMC, AGRP and NPY mRNA [ 3 4 5 9 ] . Seven micrograms of total RNA from adipose tissue was also subjected to Northern blot analysis to measure leptin mRNA.


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