Words similar to agrp
Example sentences for: agrp
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However, adrenalectomy completely blocked the elevation of AGRP mRNA in diabetic mice whether or not they were fasted (Fig.
Taken together, these data suggest that elevated glucocorticoids are sufficient to drive the increase in hypothalamic AGRP mRNA during fasting and diabetes but not the reduction in POMC mRNA.
However, the corticosterone implants produced the unexpected effect of elevating hypothalamic POMC mRNA, a rare if not unique circumstance in which hypothalamic AGRP and POMC mRNA are regulated in the same direction.
Adrenalectomy has been reported to block elevations in NPY mRNA in response to fasting [ 14 ] . On the other hand, it has been reported that elevation of plasma corticosterone levels is not required for the induction of NPY mRNA by fasting [ 15 ] . In addition, the extent to which hypothalamic AGRP and POMC mRNA depends on elevated glucocorticoid levels in fasting and insulin deficiency has not been determined to date.
The high-fat diet did not significantly influence hypothalamic AGRP in this study, but surprisingly adrenalectomy slightly stimulated hypothalamic AGPR mRNA levels (Fig.
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