Example sentences for: agrp

How can you use “agrp” in a sentence? Here are some example sentences to help you improve your vocabulary:

  • This elevation in hypothalamic POMC with only a very modest increase in the antagonist AGRP mRNA (Fig.

  • As with AGRP mRNA, NPY mRNA was elevated in diabetic mice, and adrenalectomy blocked this induction of NPY mRNA in diabetic mice whether or not they were fasted (Fig.

  • Interestingly, at least with respect to food intake and body weight over this 48-hour period, the elevation of POMC appears to compensate for the elevation in AGRP to produce no net functional effect on body weight homeostasis in the presence of significantly elevated plasma corticosterone.

  • On the other hand, blocking the rise in corticosterone by adrenalectomy prevented the reduction in hypothalamic POMC mRNA and the induction of AGRP mRNA, without reversing either the reduced leptin or the reduced adiposity, characteristic of insulin-deficient diabetic mice (Fig.

  • Adrenalectomy has been reported to block elevations in NPY mRNA in response to fasting [ 14 ] . On the other hand, it has been reported that elevation of plasma corticosterone levels is not required for the induction of NPY mRNA by fasting [ 15 ] . In addition, the extent to which hypothalamic AGRP and POMC mRNA depends on elevated glucocorticoid levels in fasting and insulin deficiency has not been determined to date.


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