Example sentences for: aged

How can you use “aged” in a sentence? Here are some example sentences to help you improve your vocabulary:

  • Since those glory days Acapulco has aged — maybe not quite as gracefully as its fans would have hoped.

  • Later: Tony Blair eats Comice pears with aged Gruyère-- c'est savoir faire .

  • A similar imbalance is seen in some 'high-turnover' conditions, including Paget's disease [ 9 17 ] . In situations of high bone turnover, the 'aged' bone matrix will rapidly be replaced with a new matrix, leading to a lower residence time (i.e.

  • In CD8 +T cells from African HIV +patients, stimulated with env peptide, both IFN-γ and TNF-α production were increased over controls [ 52 ] . PBMC from the elderly (almost healthy donors) showed upregulation of TNF-α in unstimulated cultures [ 52 ] . HLA-DR activation of CD8 +CD57 +cells from elderly subjects strongly produced TNF-α [ 48 ] . Lipopolysaccharide-activation of T cells from aged donors induced higher levels of TNF-α than controls in two separate studies [ 53 31 ] . Finally, in HIV +patients receiving HIV type 1 antigen, both INF-γ and TNF-α were significantly increased in memory T cells activated by antigen [ 54 ] .

  • Our data show that the HIV +and aged conditions foster a change in the CD8 +T cell repertoire characterized by expansion of a CD8 +CD28 -phenotype capable of enhanced IFN-γ and TNF-α production.


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