Example sentences for: age-bsa

How can you use “age-bsa” in a sentence? Here are some example sentences to help you improve your vocabulary:

  • First, we identify a new functional role for CD36 as an essential mediator of proximal tubular epithelial apoptosis, inducible by AGE-BSA, CMLmin-BSA, and FFA PA.

  • Because AGE-BSA glycated for 5 wk (AGE-BSA5) induced robust apoptosis at concentrations between 20 and 40 μM (Figure 4A), we chose this preparation and concentration for further analysis in all subsequent experiments.

  • Both AGE-BSA5 and PA increased phospho-src levels rapidly (after as little as 5 min), and over a prolonged time interval (up to 3 h) (Figure 5A and 5B).

  • AGE-BSA5-induced apoptosis was blocked when cells were preincubated with neutralizing anti-CD36 antibody, while preincubation with control IgG antibody had no effect (Figure 4A).

  • Together these findings indicate that CD36 receptor mediates sequential phosphorylation of src kinases and p38 MAPK, leading to activation of caspase 3 and apoptosis in human PTECs exposed to AGE-BSA and PA ligands.


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