Example sentences for: age-bsa

How can you use “age-bsa” in a sentence? Here are some example sentences to help you improve your vocabulary:

  • In contrast, AGE-BSA significantly increased apoptotic nuclei compared with unglycated BSA in MCT PTECs transiently transfected with CD36 expression vector (Figure 6).

  • AGE-BSA5 treatment had no significant effect on rates of apoptotic nuclei in MCT PTECs transfected with control vector (Figure 6).

  • Our finding that AGE-BSA and PA induce apoptosis through a CD36-mediated and p38- and caspase-dependent mechanism in tubular epithelial cells, similar to TSP-1 and ox-LDL in endothelial cells and macrophages, respectively, suggests that multiple, context-dependent extracellular stimuli of apoptosis may converge on CD36 scavenger receptor to activate src kinase and proapoptotic p38 MAPK pathway.

  • Together these findings indicate that CD36 receptor mediates sequential phosphorylation of src kinases and p38 MAPK, leading to activation of caspase 3 and apoptosis in human PTECs exposed to AGE-BSA and PA ligands.

  • Taken together, our findings demonstrate that pathophysiologically relevant species of AGE-BSA and CML-BSA, as well as saturated FFA PA, induce apoptosis in human PTECs at concentrations previously observed in plasma and/or urine in humans with diabetes.


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