Words similar to age-bsa
Example sentences for: age-bsa
How can you use “age-bsa” in a sentence? Here are some example sentences to help you improve your vocabulary:
First, we identify a new functional role for CD36 as an essential mediator of proximal tubular epithelial apoptosis, inducible by AGE-BSA, CMLmin-BSA, and FFA PA.
Because AGE-BSA glycated for 5 wk (AGE-BSA5) induced robust apoptosis at concentrations between 20 and 40 μM (Figure 4A), we chose this preparation and concentration for further analysis in all subsequent experiments.
Both AGE-BSA5 and PA increased phospho-src levels rapidly (after as little as 5 min), and over a prolonged time interval (up to 3 h) (Figure 5A and 5B).
AGE-BSA5-induced apoptosis was blocked when cells were preincubated with neutralizing anti-CD36 antibody, while preincubation with control IgG antibody had no effect (Figure 4A).
Together these findings indicate that CD36 receptor mediates sequential phosphorylation of src kinases and p38 MAPK, leading to activation of caspase 3 and apoptosis in human PTECs exposed to AGE-BSA and PA ligands.