Words similar to age-bsa

Example sentences for: age-bsa

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Treatment with AGE-BSA for 2, 5, or 10 wk or with CML-BSA induced a significant increase in the number of apoptotic nuclei in CD36-positive HK-2 cells compared with control BSA-treated or untreated HK-2 cells (Figure 4A).
Because AGE-BSA glycated for 5 wk (AGE-BSA5) induced robust apoptosis at concentrations between 20 and 40 μM (Figure 4A), we chose this preparation and concentration for further analysis in all subsequent experiments.
Therefore we examined phospho-src, phospho-p38 levels and caspase 3 activation in HK-2 PTECs treated with AGE-BSA and PA in the absence or presence of anti-CD36 neutralizing antibody.
AGE-BSA5-induced apoptosis was blocked when cells were preincubated with neutralizing anti-CD36 antibody, while preincubation with control IgG antibody had no effect (Figure 4A).
To test whether CD36 was sufficient to mediate AGE-BSA-induced apoptosis, we transfected CD36-negative mouse MCT PTECs with a plasmid expressing human CD36 or empty control vector, followed by treatment with control BSA or AGE-BSA5.