Example sentences for: adoptive

How can you use “adoptive” in a sentence? Here are some example sentences to help you improve your vocabulary:

  • Although the mechanism of the contralateral effect is unclear, we have demonstrated that adoptive transfer of dendritic cells from animals treated with adenovirus-mediated gene transfer of v-IL-10 to untreated immunized animals is able to confer a therapeutic effect (unpublished data).

  • It is unclear at present how immune responses to Ad-transduced T cells might affect their in vivo function, but the ability to examine early in vivo responses following adoptive transfers for even 3-4 days should prove valuable, and transfers into immune-deficient recipients should facilitate long-term in vivo studies.

  • To further investigate the effects of adenoviral transduction on T cell biology, and to examine the possibility that hCAR expression (an Ig superfamily member of undetermined function) might alter the in vivo distribution of transduced T cells, we examined the tissue distribution of DO11.hCARΔcyt T cells following adoptive transfer into BALB/c recipients.

  • Indeed, the CD4+ T cells that directly destroy MHCII-positive tumors were identified [ 5 ] . In the clinic, the expression of MHCII on colorectal carcinomas is correlated with more favourable prognosis [ 6 ] . Adoptive transfer studies show that ex vivo activated CD4+ T cells are able to recognize, and to eliminate, MHCII-positive tumors either by themselves [ 7 ] or in co-operation with CD8+ T cells [ 8 ] . It has been also demonstrated that the increased MHCII expression on tumor cells and macrophages following treatment with IFNg in vivo was associated with enhanced efficacy of adoptive T cell therapy in a mouse model of metastatic sarcoma [ 9 ] .

  • Moreover, by focusing on postadolescence divergence of socioeconomic position, the study avoided concerns affecting comparisons of twins raised separately versus together, e.g., difficulties in assessing similarities versus differences of the family of origin versus adoptive family [4–6].


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