Words similar to adipocyte
Example sentences for: adipocyte
How can you use “adipocyte” in a sentence? Here are some example sentences to help you improve your vocabulary:
C/EBPα binds to and activates transcription of the gene promoter for the p21 inhibitor of cyclin-dependent kinase (CDK) [ 37 ] . This led to speculation that p21 gene activation may contribute to cell cycle arrest by C/EBPα [ 37 ] . Similarly, suppression of mitotic growth during adipocyte differentiation was associated with C/EBPα activation of the promoters of gadd45 (growth arrest and DNA damage-inducible gene 45), gas2 and gas3 (growth arrest-associated genes 2 and 3) [ 5 6 38 39 ] . However, C/EBPα mutants defective in DNA binding still blocked proliferation [ 25 33 ] . This suggested that direct promoter activation was unnecessary, or redundant, for C/EBPα proliferation arrest [ 18 ] .
Leptin production is primarily regulated by insulin-induced changes in adipocyte metabolism—its secretion levels correlate with adipocyte mass and lipid loads.
One possibility is that hormones secreted by adipocytes compromise peripheral insulin sensitivity, and a number of candidates for such adipocyte signals have been identified.
While habitual physical activity promotes a great variety of physiological adaptations that alter vascular reactivity, cardiac function, adipocyte function, and neurophysiology, adaptive responses of skeletal myofibers confer at least some of the health benefits.
Tang and Lane [ 49 ] showed that C/EBPα becomes associated with peri-centromeric chromatin upon expression during adipocyte differentiation.