Words similar to ad-transduced
Example sentences for: ad-transduced
How can you use “ad-transduced” in a sentence? Here are some example sentences to help you improve your vocabulary:
reported accelerated loss of Ad-transduced cells relative to controls via an immune-mediated mechanism [ 15 ] suggesting limitations for long-term adoptive transfer studies into immune-competent recipients.
Ad-transduced DO11.hCARΔcyt trafficked normally to secondary lymphoid organs following adoptive transfer, indicating that neither hCARΔcyt nor adenoviral transduction altered normal in vivo migration patterns.
Thus, there was no preferential loss or increase of the Ad-transduced cells in vivo, nor were there gross differences in trafficking to secondary lymphoid tissues.
It is unclear at present how immune responses to Ad-transduced T cells might affect their in vivo function, but the ability to examine early in vivo responses following adoptive transfers for even 3-4 days should prove valuable, and transfers into immune-deficient recipients should facilitate long-term in vivo studies.
Flow cytometric analysis determined that the transferred population of Ad-transduced cells from DO11.hCARΔcyt Tg donors retained the pre-transfer frequencies of GFP +and GFP -cells within the DO11.
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