Example sentences for: actin-binding

How can you use “actin-binding” in a sentence? Here are some example sentences to help you improve your vocabulary:

  • The fusion protein was then cleaved with thrombin (Calbiochem, San Diego, CA) to yield the actin-binding domain of α-actinin and the GST carrier.

  • Because gravin has a putative actin-binding domain, it is likely that the association is with actin.

  • As described previously [ 6 ] , a pGEX2 vector, encoding the actin-binding domain, residues 2-269 of chicken smooth muscle α-actinin, fused with the carboxy terminus of glutathione S-transferase (GST) with an engineered thrombin cleavage site, was kindly provided by Dr DR Critchley of the University of Leicester, UK.

  • Localization studies and visualization of the actin cytoskeleton in live cells with an actin-binding protein tagged with green fluorescent protein (GFP) indicate that the organization of F-actin changes during trichome morphogenesis [ 33, 34].

  • The BTB domain is a highly conserved 120 amino acid, hydrophobic-rich, protein-protein interaction domain that mediates homodimerization and heterodimerization of a large number of proteins with diverse functions [ 9 ] . The three dimensional structure of one BTB domain [ 33 ] has been characterized through structure-function studies [ 34 ] . Proteins containing BTB domains are currently categorized into three groups [ 35 ] : 1) DNA-binding proteins often containing zinc fingers in the C-terminal region, 2) actin binding proteins that contain a kelch repeat of ~50 residues that terminate in a pair of glycine residues [ 36 ] and 3) proteins that have neither an actin-binding domain nor a DNA-binding domain.


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