Example sentences for: acta

How can you use “acta” in a sentence? Here are some example sentences to help you improve your vocabulary:

  • To this end, we have examined the global transcriptional response of a human intestinal epithelial cell line, Caco-2, to infection by L. monocytogenes and isogenic mutants which are disrupted in the actA or prfA gene.

  • The actA internal in-frame deletion mutant (DP-L1942) [ 30], which cannot initiate the polymerization of actin, was used to assess transcriptional responses specific to the motility phase of infection.

  • Three strains of L. monocytogenes were used; wild type (10403S), a mutant for the transcriptional regulation of virulence genes, prfA (DP-L1075) [ 33], and a mutant deficient for intracellular motility, actA (DP-L1942) [ 30].

  • To this end, we carried out similar 8-hour time courses with an isogenic L. monocytogenes strain deficient in actA (DP-L1942, Δ actA ), which is unable to nucleate actin polymerization and hence has no capacity for intracellular motility and intercellular spread [ 30].

  • It is likely that differences in the transcriptional program would emerge at later stages of infection, as wild-type and actA bacteria replicate and kill the cells, and prfA do not.


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