Words similar to acta

Example sentences for: acta

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The actA internal in-frame deletion mutant (DP-L1942) [ 30], which cannot initiate the polymerization of actin, was used to assess transcriptional responses specific to the motility phase of infection.
To this end, we carried out similar 8-hour time courses with an isogenic L. monocytogenes strain deficient in actA (DP-L1942, Δ actA ), which is unable to nucleate actin polymerization and hence has no capacity for intracellular motility and intercellular spread [ 30].
Microarray analysis of the actA time courses revealed that the host transcriptional responses were remarkably similar to those observed during infection with the wild-type strain.
Three strains of L. monocytogenes were used; wild type (10403S), a mutant for the transcriptional regulation of virulence genes, prfA (DP-L1075) [ 33], and a mutant deficient for intracellular motility, actA (DP-L1942) [ 30].
The three measurements of log 2 (Caco-2 T 0 /reference) from the parallel set were averaged to define the pattern of expression in uninfected cells at the beginning of the synchronized parallel time course, and was then used to zero transform the mock, wild-type, actA and prfA parallel infections.