Words similar to acr
Example sentences for: acr
How can you use “acr” in a sentence? Here are some example sentences to help you improve your vocabulary:
Except for the tender-joint count, none of the observed disease activities was statistically different from placebo according to the ACR criteria at the 20% improvement level.
The endpoint used to characterize clinical activity was the proportion of patients whose disease improved according to the 20% ACR criteria [ 16].
E174 in ACR3 and S218 in ACR4 are required for catalytic function [ 12 ] . Substitution of H59 in ACR1 converted CD39 into an ADPase in a quaternary structure dependent manner [ 13 ] . Mutation of W187A in ACR3 affected CD39 folding and translocation, while mutation of W459A in ACR5 increased ATPase activity but diminished ADPase activity [ 14 ] . Mutations of D62 and G64 of ACR1 and D219 and G221 of ACR4 demonstrated that the nucleotide phosphate binding domains of NTPDases are similar to those present in the actin/heat shock protein/sugar kinase superfamily [ 15 ] . These results suggest that the conserved residues of the ACR1 to 5 regions are involved in the catalytic mechanism of CD39.
An analogous genetic system ( Arr or ACR ) has also been described in the eukaryote Saccharomyces cervisiae [ 24 ] . Thus the ars operon, or similar arsenic resistance systems, appears to be relatively widespread throughout microorganisms.
Residues of ACR1 to ACR5 of CD39 have been mutated to study the involvement of the ACR regions in catalysis.
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