Words similar to acr

Example sentences for: acr

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E174 in ACR3 and S218 in ACR4 are required for catalytic function [ 12 ] . Substitution of H59 in ACR1 converted CD39 into an ADPase in a quaternary structure dependent manner [ 13 ] . Mutation of W187A in ACR3 affected CD39 folding and translocation, while mutation of W459A in ACR5 increased ATPase activity but diminished ADPase activity [ 14 ] . Mutations of D62 and G64 of ACR1 and D219 and G221 of ACR4 demonstrated that the nucleotide phosphate binding domains of NTPDases are similar to those present in the actin/heat shock protein/sugar kinase superfamily [ 15 ] . These results suggest that the conserved residues of the ACR1 to 5 regions are involved in the catalytic mechanism of CD39.
An analogous genetic system ( Arr or ACR ) has also been described in the eukaryote Saccharomyces cervisiae [ 24 ] . Thus the ars operon, or similar arsenic resistance systems, appears to be relatively widespread throughout microorganisms.
Of note, a large epidemiologic study of patients with early inflammatory arthritis found that the proportion of patients who met the ACR criteria increased if the criteria were applied cumulatively over a 5 year period [ 29].
Figure 1describes the data using the 20% ACR criteria for response at the various doses or schedules tested.
We utilized the accepted definition of RA using the 1987 ACR criteria [ 27].