Words similar to acr

Example sentences for: acr

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Residues of ACR1 to ACR5 of CD39 have been mutated to study the involvement of the ACR regions in catalysis.
Figure 1describes the data using the 20% ACR criteria for response at the various doses or schedules tested.
Of note, a large epidemiologic study of patients with early inflammatory arthritis found that the proportion of patients who met the ACR criteria increased if the criteria were applied cumulatively over a 5 year period [ 29].
We utilized the accepted definition of RA using the 1987 ACR criteria [ 27].
NTPDases do not form phosphorylated intermediates during catalysis, a conclusion also supported by lack of vanadate sensitivity and Pi product inhibition [ 3 4 5 6 ] . The catalytic reaction appears to be irreversible and no partial reactions have been observed [ 7 8 ] . Divalent cations like Ca 2+or Mg 2+are required for activity, and maximal activity is reached when the concentrations of substrates and divalent cations are equal [ 1 ] . The specific activities of NTPDases vary over a broad range from ten thousand units for potato apyrase to less than one hundred units for chicken gizzard ecto-ATPase [ 9 10 ] . Sequence comparisons indicate that most of NTPDases contain five highly conserved regions, apyrase conserved region, ACR1 - ACR5 [ 9 11 ] . However, the catalytic sites have not been identified, although ACR1 and ACR4 have been implicated in β- and γ-phosphate binding, respectively [ 9 ] .