Example sentences for: acetyltransferase

How can you use “acetyltransferase” in a sentence? Here are some example sentences to help you improve your vocabulary:

  • Visual examination of the structure of this insert domain revealed a topology with elements of both a sandwich and a barrel, and two "waist"-like structures that are characteristic of the sandwich-barrel hybrid motif (SBHM) fold [ 75 76 ] (see also the SCOP database [ 65 ] ). The SBHM fold is present in biotin/lipoate carrier domains and their homologs found in a variety of enzymes and transporters [ 76 ] . A DALI search with this insert domain from the β subunit of Thermus DDRP showed similarity to the SBHMs from various biotin/lipoate-binding enzymes, such as acetyl-CoA carboxylase (1bdo) or dihydrolipoamide acetyltransferase (1iyu) with Z scores of ~6 and RMSD ~2.

  • The transcriptional regulatory activities of Smad1 in the nucleus are associated with its ability to directly bind to DNA [ 12 ] , its interaction with other DNA-binding transcription factors, such as OAZ, SIP1 and Hoxc-8 [ 13 14 15 ] , and also its interaction with the master transcriptional co-activator CBP/p300 [ 16 ] . Smad4 is an essential functional partner in Smad-regulated transcription and also interacts with CBP/p300 via a domain within the central linker region named as SAD (Smad Activation Domain) [ 13 ] . Since CBP/p300 has intrinsic histone acetyltransferase (HAT) activity and participates in chromatin remodeling, the recruitment of CBP/p300 into the DNA-binding complexes of Smad1 and Smad4 is likely a critical step in Smad-regulated gene activation.

  • Not surprisingly, these enzymes clustered according to specific enzymatic function of the different classes of acetyltransferase.

  • Aside from induction of ICER, Tat is capable of forming complex (es) with a component of TFIID, TAF II 250 [ 24 ] and Tip60 [ 25 ] both of which contain histone acetyltransferase (HAT) activity.

  • Mesorhizobium dihydrolipoamide acetyltransferase, E = 10 -3, iteration 4).


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