Words similar to abp-tg

Example sentences for: abp-tg

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The number of primary spermatocytes undergoing apoptosis in ABP-TG mice relative to controls was decreased after 60 days; the decrease was statistically significant on days 90, 240 and 360 (Figure 5C& Table 2).
[ 51 ] described meiotic arrest and an "increased occurrence of apoptosis" of testicular germ cells (primarily pachytene spermatocytes and cells in metaphase) in 3-, 6-, and 12-month old ABP-TG mice and suggested that these events were the cause of the fertility impairment seen in these animals.
The present study was performed to provide quantitative data on germ cell apoptosis in control and in ABP-TG mice aged from 7 to 360 days.
It is well established that TG mice overexpressing rat ABP [ 22 ] develop a testicular impairment [ 23 24 25 ] leading gradually to a reduced number of germ cells and infertility [ 26 ] . Various theories were proposed to explain the possible mechanisms behind this testicular impairment seen in the ABP-TG mice overexpressing rat ABP.
Between Days 21 and 60, the number of S-phase cells undergoing apoptosis was significantly higher in ABP-TG than in control mice.