Words similar to abp

Example sentences for: abp

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Transgenic mice over-expressing rat ABP in their testes were developed by Reventos et al.
The initial increase seen in germ cell apoptosis (especially at 21 and 30 days) is likely to result from a direct or indirect action of ABP and may affect the subsequent life-death balance of germ cell populations in TG mice.
However, at this point it is not clear whether ABP regulates this apoptotic wave by direct action on germ cells or indirectly, by reducing the intra-testicular concentrations of free (bioavailable) T. The known biochemical properties and actions of ABP make the second mechanism more likely (see Jeyaraj et al.
Our data indicate that the presence of greater than physiological concentration of ABP in the mouse testis has a biphasic effect on the frequency of apoptosis in germ cells.
, [ 10 12 13 14 15 ] ]. It is thought to regulate spermatogenesis and sperm maturation by maintaining high androgen levels in the testis and epididymis [ 16 17 ] and has been proposed as a biochemical marker for Sertoli cell function and formation of blood-testis barrier [ 12 18 ] . More recently, cell surface receptors for ABP and its liver-derived homolog sex hormone-binding globulin (SHBG) were identified in several androgen target tissues, suggesting that these extracellular steroid-binding proteins may have a much broader, hormone-like function [ 19 20 21 ] .