Words similar to abp

Example sentences for: abp

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The increased concentration of ABP present in the testes of TG mice (see Joseph et al . [ 25 ] ) will chronically reduce the concentration of intra-testicular free T available for interaction with androgen receptor (AR) and other molecular targets.
Androgen binding protein (ABP) is produced by Sertoli cells of the testis, secreted into the lumen of seminiferous tubules, and transported with tubular fluid to the epididymis, where it is internalized and degraded by the epithelial cells of the initial segment and the caput; it binds testosterone (T), dihydrotestosterone and estradiol with high affinity [ 9 10 11 ] . The functions of ABP have been the subject of many reviews [e.g.
The initial increase seen in germ cell apoptosis (especially at 21 and 30 days) is likely to result from a direct or indirect action of ABP and may affect the subsequent life-death balance of germ cell populations in TG mice.
Transgenic mice over-expressing rat ABP in their testes were developed by Reventos et al.
However, at this point it is not clear whether ABP regulates this apoptotic wave by direct action on germ cells or indirectly, by reducing the intra-testicular concentrations of free (bioavailable) T. The known biochemical properties and actions of ABP make the second mechanism more likely (see Jeyaraj et al.