Words similar to abasic
Example sentences for: abasic
How can you use “abasic” in a sentence? Here are some example sentences to help you improve your vocabulary:
The abasic sugar-phosphate backbone is then cleaved by an apurinic/apyrimidinic endonuclease or lyase.
This redundancy of binding to the 3' side is unique to APE, as is its strong binding to the DNA opposite the abasic site.
Is the specificity of APE determined by binding 3' to an abasic site?
The endonuclease activity of DNase 1 is reduced many fold by integrating this loop from E. coli exonuclease III, but the mutant cleaves at abasic sites in DNA with low efficiency [ 29 ] . Thus additional residues in the APEs control specificity while still allowing a reasonable rate of phosphorolytic cleavage.
APEs are essential for mammalian cell growth and bacterial survival in the presence of ionizing radiation and DNA mutagens [ 6 ] . They initiate repair of an abasic DNA site by cleaving the phosphodiester backbone 5' of the phosphodeoxyribose.
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