Example sentences for: a-gvhd

How can you use “a-gvhd” in a sentence? Here are some example sentences to help you improve your vocabulary:

  • Cryptitis and crypt abscesses are not feature of A-GVHD and should be differentiated from "popcorn lesions", which show apoptotic cells instead of neutrophils along the crypt lining and in the crypt lumen.

  • Patients with cutaneous and hepatic A-GVHD frequently have apoptosis in their colon biopsies, without any intestinal symptoms [ 4 ] . This may represent sub-clinical intestinal A-GVHD if the apoptosis is observed in relation to the crypts [ 10 ] . If other findings (Table 4) are present in the absence of crypt apoptosis, it may represent evidence of past A-GVHD or due to other etiologic factors such as chronic infections and inflammatory bowel disease.

  • In addition to other histopathological features described in association with A-GVHD, significance of apoptosis, crypt abscess, and crypt loss has been emphasized [ 4 11 12 13 14 15 ] . However, the distribution pattern of apoptosis in colonic mucosa in A-GVHD has not been methodically evaluated.

  • 'Cryptitis' has been described in association with A-GVHD, but these studies do not define the term [ 6 12 13 ] . Although reference had been made to crypt abscesses in these reports, it is evident that the researchers were looking at the apoptotic debris in gland lumina and suggested 'crypt abscess-like' changes [ 14 ] . In our study, only one case (2.

  • Other features observed more often in A-GVHD with statistically significant differences as compared to the negative control groups included (Table 2and 4, Figure 2): pericryptal apoptosis adjacent to the crypts in LP, crypt abnormalities (including crypt size variation, crypt dilatation and irregular crypt distribution), reactive changes in LP (including reduced mucosal thickness, muciphages in LP, increased microvessel network, and focal fibrosis), and reactive changes in the surface epithelium with mucin depletion.


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