Words similar to proteases
Example sentences for: proteases
How can you use “proteases” in a sentence? Here are some example sentences to help you improve your vocabulary:
Activated Kupffer cells and neutrophils release ROIs and proteases in response to inflammatory cytokines in the liver [ 21].
Recent studies in genetically altered mice have suggested an important role for multiple proteases in the development of emphysema.
One of great importance, urokinase (uPA) and its high affinity receptor, the GPI-anchored membrane CD87 (uPAR), is critical in tumour progression and its level of expression is correlated with poor prognosis of various cancers such as prostate [ 2 ] , breast [ 3 ] , colon [ 4 ] , ovarian [ 5 ] , gastric [ 6 ] , brain [ 7 ] , and lung cancer [ 8 ] . Urokinase (uPA) and its main product plasmin belong to the very early proteases [ 9 10 11 ] that activate the metallo-protease (MMP) cascade and therefore control cell motility, tissue remodelling and the activation of various angiogenic factors (VEGF, TGFβ).
An alternative mechanism for the formation of inclusion bodies in protein conformation disorders is suggested by a recent study showing that clearance of poly-Gln and poly-Ala inclusions is accelerated by compounds like rapamycin, which stimulate protein degradation by autophagy [ 64 ] . Along similar lines, the work of Kegel et al . [ 65 ] hints that poly-Gln huntingtin may be degraded mainly in autophagic vacuoles containing lysosomal proteases.
This compound, now a drug candidate, was originally synthesized by Dr. Jim Palmer of Khepri Pharmaceuticals (now Celera) as part of an industry search for anti-inflammatory and anticancer drugs focusing on cysteine proteases.
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