Example sentences for: orthology

How can you use “orthology” in a sentence? Here are some example sentences to help you improve your vocabulary:

  • Similarly to the issues described in the previous section, the detection of such examples is complicated by the fact that for many cases in which a discrepancy between orthology bootstrap values and sequence similarity exists, all sequences in the Pfam alignment appear to have to same function, the Pfam family is lineage specific, or the annotations are too poor/confusing to make any kind of inference.

  • Furthermore, the same results are achieved whether only the top 1 sequence (the one with the highest orthology value, shown in Tables 2and 3) or the top 10 sequences are used to transfer annotation from.

  • Next, we determined the distribution of the top orthology bootstrap values.

  • Storm, Sonnhammer, and colleagues have recently developed similar ideas and procedures in a program called ORTHOSTRAPPER [ 44 45 ] . One distinction between the two approaches is that ORTHOSTRAPPER's orthology determination procedure does not employ a species tree for duplication inference; it uses a heuristic based on sequence similarity rather than a formally correct phylogenetic means of inferring orthology.

  • We were next interested in the number of sequences in the two proteomes for which the orthology bootstrap values do not correspond to sequence similarity (Table 5).


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