Example sentences for: orthology

How can you use “orthology” in a sentence? Here are some example sentences to help you improve your vocabulary:

  • We were able to resolve orthology for Rh4 only, as the sina gene in A. gambiae is contained within the Rh4 gene as in D. melanogaster and other species in the subgenus Sophophora .

  • Only two of the 560 protein-coding genes that show clear orthology between E. coli and Buchnera would have been removed (due to absence from both Vibrio cholerae and Yersinia pestis ). The two genes ( dnaC and dnaT ) are linked in both Buchnera and E. coli and were retained in the ancestor.

  • Orthology was assessed using reciprocal BLAST searches of the public protein database; those sequences receiving high scores in each search were also analyzed phylogenetically to ensure orthology.

  • Careless use of orthology relationships without examining the tree itself can lead to incorrect annotations.

  • In many cases a discrepancy between orthology bootstrap values and sequence similarity is caused by orthologs in only phylogenetically distant (relatively to the query sequence) species.


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