Words similar to immunosuppressive
Example sentences for: immunosuppressive
How can you use “immunosuppressive” in a sentence? Here are some example sentences to help you improve your vocabulary:
Cyclosporine (CsA) and tacrolimus (TAC) are the primary immunosuppressive drugs used for the prevention of acute rejection after renal transplantation.
Maintenance immunosuppressive medication use, in particular cyclosporine and tacrolimus, at the time of discharge after transplantation was also analyzed as a preexisting covariate.
In addition to the immunosuppressive toxicities, other risks are associated with the islet transplant procedure itself, including intra-abdominal hemorrhage following the transplant, and portal vein thromboses.
The selective suppression of Th1 cell activity is believed to be due to IL-10 inhibition of IL-12, a differentiation factor for Th1 cells [ 11 12 ] . The release of reactive oxygen and nitrogen intermediates by macrophages is also suppressed by IL-10 [ 13 14 ] . In addition, IL-10 stimulates the production of cytokine inhibitors such as IL-1 receptor antagonist [ 15 ] . In patients with rheumatoid arthritis, IL-10 is produced by synovial membrane cells and is found at high levels in the synovial fluid [ 16 17 ] . It has been shown that suppression of IL-10 production by synovial cells is associated with increased levels of IL-1 and TNF-α, suggesting that IL-10 plays a suppressive role in rheumatoid arthritis joints [ 16 ] . It was also observed that IL-10 directly stimulated proteoglycan synthesis and reversed the cartilage degradation induced by activated mononuclear cells [ 18 ] . These immunosuppressive activities indicate that IL-10 is a potential therapeutic approach for autoimmune diseases.
The addition of SRL to the immunosuppressive regimen of Tac resulted in decreased lymphocyte proliferation exhibiting decreased allo-immune response.