Example sentences for: immunosuppressive

How can you use “immunosuppressive” in a sentence? Here are some example sentences to help you improve your vocabulary:

  • Information on use of medications (other than immunosuppressive medications), alcohol, tobacco, or radiologic procedures was not available.

  • In some circumstances, CD4 +and CD8 +T cells were rendered inactive in tumor-bearing hosts [ 8 ] . The inactivation of CD4 +T cells has been attributed either to the tumor cells themselves or to bone marrow-derived cells [ 9 10 11 ] , whereas antigen ignorance or loss of memory have been postulated to underlay that of CD8 +T cells [ 12 13 ] . Other studies have suggested that tumor cells can secrete immunosuppressive factors such as TGF-β or express Fas ligand to induce apoptosis of infiltrating lymphocytes [ 14 15 16 ] . Furthermore, the tumor vasculature appears to be quite different from normal blood vessels, in terms of structural organization, interstitial pressure, and flow patterns [ 17 ] , and in reduced lymphocyte and natural killer cell homing and adhesion [ 18 19 20 21 ] . The existence of significant barriers to effective immunological destruction is further illustrated by a mouse model of concurrent multistage tumorigenesis and anti-oncogene autoimmunity, wherein progenitor dysplastic lesions are infiltrated and disrupted, while solid tumors are not [ 22 ] . The hypothesis is that the microenvironment of certain types of solid tumor can serve to locally suppress T cell infiltration.

  • Of the seven patients, five subjects had advanced lung fibrosis and were receiving prednisone ± immunosuppressive agents; 2 patients were at an earlier stage of their disease and were not receiving immunosuppressive drugs.

  • Anti-neoplastic/immunosuppressive agents were the most common cause of poisonings in this population, as would be expected.

  • The addition of SRL to the immunosuppressive regimen of Tac resulted in decreased lymphocyte proliferation exhibiting decreased allo-immune response.


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