Words similar to immunosuppressive
Example sentences for: immunosuppressive
How can you use “immunosuppressive” in a sentence? Here are some example sentences to help you improve your vocabulary:
The current study almost certainly underestimates the incidence of serious immunosuppressive drug toxicity in this population.
Thirty intervals of care were excluded from the analysis because they occurred in subgroups with very small numbers of patients, within which it would have been impossible to obtain stable disease-specific estimates (HIV (4 men; 2 women); chronic renal disease (5 men; 7 women) and immunosuppressive therapy (3 men; 10 women)).
The selective suppression of Th1 cell activity is believed to be due to IL-10 inhibition of IL-12, a differentiation factor for Th1 cells [ 11 12 ] . The release of reactive oxygen and nitrogen intermediates by macrophages is also suppressed by IL-10 [ 13 14 ] . In addition, IL-10 stimulates the production of cytokine inhibitors such as IL-1 receptor antagonist [ 15 ] . In patients with rheumatoid arthritis, IL-10 is produced by synovial membrane cells and is found at high levels in the synovial fluid [ 16 17 ] . It has been shown that suppression of IL-10 production by synovial cells is associated with increased levels of IL-1 and TNF-α, suggesting that IL-10 plays a suppressive role in rheumatoid arthritis joints [ 16 ] . It was also observed that IL-10 directly stimulated proteoglycan synthesis and reversed the cartilage degradation induced by activated mononuclear cells [ 18 ] . These immunosuppressive activities indicate that IL-10 is a potential therapeutic approach for autoimmune diseases.
Current immunosuppressive regimens are capable of preventing islet failure for months to years, but the agents used in these treatments are expensive and may increase the risk for specific malignancies and opportunistic infections.
Of the seven patients, five subjects had advanced lung fibrosis and were receiving prednisone ± immunosuppressive agents; 2 patients were at an earlier stage of their disease and were not receiving immunosuppressive drugs.
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