Words similar to heptad

Example sentences for: heptad

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Coiled-coil domains are protein oligomerization motifs, which consist of two or more alpha helices that twist around one another to form a supercoil [ 1 ] . Peptides with the capacity to form coiled coils are characterized by a heptad repeat pattern in which residues in the first and fourth position are hydrophobic, and residues in the fifth and seventh position are predominantly charged or polar.
The first class is comprised of short coiled-coil domains of six or seven heptad repeats, also called leucine zippers.
The outer surface of the coiled-coil contains grooves into which three heptad repeat regions from the C-terminal part of the gp41 ectodomain pack, resulting in a stable six-helix bundle [ 42 45 46 47 48 49 50 51 52 53 54 ] . The six-helix bundle structure can be detected by specific antibodies [ 14 20 43 55 ] .
The principal changes are the substitution of either tyrosine or phenylalanine for leucine at the beginning of the third heptad repeat and the addition of a second proline adjacent to the first in the second heptad repeat.
The absence of any consistent pattern of heptad hydrophobic repeats indicates that there is little or no α-helical coiled-coil structure in the domain.