Words similar to anchorage-dependent

Example sentences for: anchorage-dependent

How can you use “anchorage-dependent” in a sentence? Here are some example sentences to help you improve your vocabulary:

In view of PTEN's potent growth-inhibitory capacity, we conclude that its induction after cell-matrix disruptions contributes to the maintenance of the anchorage-dependent phenotype of normal cells.
In view of PTEN's potent growth-inhibitory capacity, we conclude from our study that the increased expression and activity of endogenous PTEN in response to the disruption of cell-matrix interactions contributes to the maintenance of the anchorage-dependent phenotype of normal cells.
The murine cell line 10T1/2 and the human cell line MDAH, both of which are anchorage-dependent fibroblasts, were detached from their tissue culture dishes and cultured further on HEMA-coated plates.
In light of the well-established growth-inhibitory effects exerted by increased levels of this phosphatase, it is reasonable to conclude that this activation of PTEN significantly contributes to the anchorage-dependent phenotype, i.e., to the inhibition of cell proliferation after detachment from matrix.
Collectively, they have established that the expression of cyclin A and cyclin D, in combination with the activity of the cyclin-dependent kinase inhibitors p21 Cip1and p27 Kip1, is a crucial determinant of anchorage-dependent cell growth culture [ 27 28 29 30 31 32 ] . However, while the above elements clearly are essential executioners of cell cycle progression, it is conceivable that other elements, directly or indirectly, might be involved in anchorage-dependent growth control as well.