Words similar to γl
Example sentences for: γl
How can you use “γl” in a sentence? Here are some example sentences to help you improve your vocabulary:
The AChBP displays a large amount of homology to the amino terminal of LGIC receptors and thus may be similar in structure [ 20 24 ] . The crystal structure of this protein reveals a loose 3 residue turn incorporating the conserved glycine residue [ 24 ] . Homologous residues in other LGIC subunits have also been identified and are shown in Figure 1. The residues identified in this study as altering binding affinity of 5-HT 3 R ligands would also be present on the same surface if this structure is present in the 5-HT 3 R. While Y140 lies somewhat outside the region identified by Chiara in the nAChR (homologous to γN107), γL109 and γL119 are homologous to Y142 and Y152 of the 5-HT 3AS R. The ability of lerisetron to interact with both Y142 and Y152 also supports the hypothesis that these two amino acids are present in a loop structure since the eight intervening residues would position Y142 and Y152 too far apart to permit them both to interact with a single ligand even if they were interacting with functional groups on opposite ends of the molecule.
A similar observation has been made for the nAChR where γS111, γY117, γL119, δR113 and δT119 of the mouse nAChR receptor and γL109 and γY111 of the torpedo nAChR are all thought to be present in the binding site [ 12 13 14 15 16 17 18 ] .
have suggested that the highly conserved nature of the glycine in this region may indicate the existence of a loop structure consisting of either γ or a loose three residue-turn in the nAChR [ 12 ] . Either of these turns would bring the two putative β-strands together such that γL109, γY111 and γS115 and γY117 are all on the same side of an antiparallel β-sheet.
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