Example sentences for: β-hairpin

How can you use “β-hairpin” in a sentence? Here are some example sentences to help you improve your vocabulary:

  • Multiple alignment-based secondary-structure prediction of the Bro-N domain reveals a core with two head-to-tail units of a β-hairpin followed by an α-helix (Figure 3).

  • Within the core the first two strands are predicted to form a β-hairpin followed by a helical region, which in turn is followed by 3 consecutive strands and single α-helix.

  • We selected it for this study because it is rapidly bactericidal, functions well at elevated physiological salt concentrations such as those that may occur in the CF lung, and has a broad spectrum of activity [ 21 22 23 ] . PG-1's antiparallel β-hairpin structure and antimicrobial activity in physiological and elevated salt concentrations are maintained by its two intramolecular cystine disulfide bonds [ 21 24 25 26 27 28 ] . The antimicrobial spectrum of PG-1 includes Chlamydia trachomatis , Candida albicans , Escherichia coli , Fusobacterium nucleatum, Haemophilus ducreyi , Listeria monocytogenes , Neisseria gonorrhoeae , Porphyromonas gingivalis , Prevotella intermedia , P. aeruginosa , and Staphylococcus aureus [ 20 22 25 29 30 31 32 ] .

  • Apparently, other amino acids with small side chains can replace the glycines while maintaining the β-hairpin conformation of the phosphate-binding loop and avoiding steric interference with ATP binding.

  • Additionally, there is a nearly invariant glycine (Figure 3) that corresponds to the beginning of strand 2 and is likely to stabilize the first β-hairpin in the structure.


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