Example sentences for: β-amyloid

How can you use “β-amyloid” in a sentence? Here are some example sentences to help you improve your vocabulary:

  • For example, PPARγ agonists were shown to protect cytokine-induced PCD in cerebellar granule cells [ 59 ] . These agents could also block the neurotoxic effects caused by β-amyloid activated microglia, and thus might be beneficial in the treatment of Alzheimer's disease [ 60 ] . In non-neuronal tissues, PPARα activation was shown to suppress both spontaneous rat hepatocyte PCD and the PCD induced by transforming growth factor-β1 [ 61 ] .

  • Normally α-synuclein is present in the synaptic nerve terminals (including those of cholinergic neurons [ 37 38 ] ) but in AD its processing is altered, causing it to be abnormally deposited in plaques composed primarily of aggregates of β-amyloid peptide [ 39 ] . However, how this abnormal turnover of α-synuclein contributes to the pathophysiology of AD remains to be determined.


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