Words similar to α-tubulin

Example sentences for: α-tubulin

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The major differences between isotype classes reside in the last 15-20 amino acids of the carboxy-termini [ 10 11 ] , and these differences have been exploited in the development of isotype-specific antibodies [ 12 13 14 ] . Mammalian microtubules are formed from a mixture of α-tubulin and β-tubulin isotype classes [ 11 15 16 ] , and the antimitotics used in chemotherapy interact primarily with β-tubulin.
The SDS-boiling method for yeast extract preparation to visualize Net1 phosphorylation state in vivo and methods for protein detection were described previously [ 8 ] . For indirect immunofluorescence, we used 1:1000 rabbit α-A190, 1:2000 rabbit α-tubulin, 1:200 rabbit α-Cdc14, 1:1000 rat YL 1/2 (against tubulin), and 1:1000 mouse monoclonal HA.
Blots of cell lysates were stripped and reprobed using antibodies specific for α-tubulin (1:10,000, Sigma).
One gene common to clear-space-related metrics (non-stained tissue, including vacuoles and hydrophic degeneration) was α-tubulin (V01227).
Their effectiveness in cancer chemotherapy is thought to be due to their ability to reduce the dynamics of microtubules in mitotic spindles, thus preventing spindle assembly and interrupting the normal movement of sister chromatids toward the spindle poles [ 3 4 5 6 7 8 9 ] . Tubulin, a 100 kDa αβ heterodimer, is structurally heterogeneous, with seven genes encoding α-tubulin and β-tubulin isotypes.