Words similar to α-secretase
Example sentences for: α-secretase
How can you use “α-secretase” in a sentence? Here are some example sentences to help you improve your vocabulary:
[58] implicated the Rho pathway in modulation of α-secretase activity while dissecting the activated shedding process that accompanies serotonergic signal transduction.
Most of this shedding is catalyzed by the α-secretase pathway, but a trace amount (<5% [49]) is catalyzed by β-secretase/β-site APP cleaving enzyme [50].
Further, we were able to demonstrate that α-secretase activity could be modulated by molecules further upstream in the isoprenoid pathway (see Figure 7).
Despite this, however, the association of statins and cholesterol levels with activated α-secretase-mediated shedding of the APP ectodomain was unexpected and not readily explicable by existing knowledge regarding regulation of α-secretase activity.
A smaller fraction of APP molecules (approximately 20% in PC12 cells under basal conditions [5]) undergoes ectodomain shedding catalyzed by either the α-secretase (nonamyloidogenic) or β-secretase (potentially amyloiodgenic) pathway.
Loading...