Example sentences for: zd

How can you use “zd” in a sentence? Here are some example sentences to help you improve your vocabulary:

  • Although it is known that the ZD domain can function as a DNA binding domain, its exact role in these individual steps of removal of a negative superhelical turn from DNA by E. coli topoisomerase I remains to be defined.

  • ZD domain was found to bind to single-stranded DNA, but not double-stranded DNA, with high affinity.

  • Top67 and the ZD domains at different concentrations were mixed and incubated at 37°C for 10 min before addition to the 0.3 μg of supercoiled plasmid DNA in 20 μl of 10 mM Tris-HCl pH 8.0, 2 mM MgCl 2 , 0.1 mg/ml gelatin.

  • The presence of the ZD domain may enhance the transition of Top67 from a closed conformation to a more open conformation so that strand passage can take place through the "DNA gate".

  • Therefore the ZD domain can supply the function that is missing in Top67 even when the two domains are not covalently linked.


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