Words similar to yaef

Example sentences for: yaef

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The NlpC/P60 superfamily has diversified into four major families, with two of them - namely the LRAT and YaeF/Poxvirus G6R families - showing a circular permutation of the catalytic domain.
All the members of the LRAT family, including the forms from RNA viruses, clearly form a distinct family which excludes the YaeF/poxvirus G6R family, which shows a similar circular permutation.
Interestingly, the eukaryotic versions typified by the LRAT, their viral homologs and the bacterial forms typified by E. coli YaeF, while containing all the hallmark signatures of the NlpC/P60 catalytic domain, showed a reversal in the positions of the motifs with the conserved cysteine and the conserved histidine in their primary structures (Figures 1, 2).
The prediction of a classical thiol-protease fold for the NlpC/P60 proteins also explains the circular permutation of the conserved motifs that is observed in several members of this superfamily such as LRAT and YaeF (Figure 1).
Reciprocal searches initiated with regions from the newly detected proteins YaeF, LRAT and LytN detected their closely related homologs in the initial iterations, but in subsequent iterations they recovered several classic N1pC/P60 homolog members with significant E-values (E < 0.01),