Words similar to xorphanol

Example sentences for: xorphanol

How can you use “xorphanol” in a sentence? Here are some example sentences to help you improve your vocabulary:

The only exceptions were the highly efficacious ligands fentanyl (P < 0.05), metazocine (P < 0.001) and xorphanol (p < 0.001).
This order was in agreement with the relative potencies of these drugs, showing that cyclazocine and xorphanol had higher affinities and potencies compared to morphine, although they were both less efficacious than morphine.
The rank order of efficacy of the ligands tested was metazocine = xorphanol ≥ fentanyl = SKF 10047 = etorphine = hydromorphone = butorphanol = lofentanil > WIN 44,441 = Nalbuphine = cyclazocine ≥ met-enkephalin >> morphine = dezocine.
This ligand had been described as a mixed agonist-antagonist opioid ligand [ 30 31 ] with agonistic activity at κ opioid receptors [ 32 ] . Overall very little work has been done on xorphanol and little is known about it except that it is an orally active analgesic with limited physical dependence liability [ 30 ] . Thus the present report describing its activity at δ opioid receptors provides useful data on this ligand.
Clinically, xorphanol is a well tolerated, orally active analgesic that provides effective pain relief but shows low physical dependence liability [ 29 30 ] . It is possible that the low physical dependence liability of this drug is due to its partial agonism at μ opioid receptors.