Words similar to xid

Example sentences for: xid

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The importance of the Tec kinases in antigen receptor signaling was first demonstrated by the observation that mutations in BTK result in the human disease X-linked agammaglobulinemia (XLA) and the murine counterpart X-linked immunodeficiency ( xid ). These severe B cell immunodeficiencies are characterized by diminished numbers of mature B cells and reduced immunoglobulin levels associated with impaired PLC-γ activation and Ca ++mobilization in response to surface IgM stimulation (sIgM) [ 8, 9, 10, 11].
PH, pleckstrin homology; PI3K, phosphoinositide 3-Kinase; SH2, Src homology-2, SH3, Src homology-3; XLA, X-linked agammaglobulinemia; xid ; x-linked immunodeficiency; TCR, T cell receptor; sIgM, surface immunoglobulin M; (GAP), GTPase-Activating Protein; GST, Glutathione S-Transferase; SDS, Sodium Dodecyl Sulfate; PBS, phosphate buffered saline; NP40, Nonidet P-40; PAGE, polyacrylamide gel electrophoresis.
Until the expression of At XID is studied, no conclusion can be made as to the validity of this intron prediction.
There is also a predicted intron of only 47 nucleotides in length (At XID) which is thought to be too short for efficient splicing.
The xid mouse, in which Btk is mutated, and the Btk knockout mouse display similar, although somewhat less severe, phenotypes [ 1].