Words similar to xenopus
Example sentences for: xenopus
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Figure 3) that there is less perfect colocalization of α-DG within AChR aggregates in the present study than reported previously (see for example [ 4 ] Figure 9 for a comparable study using Xenopus muscle cell cultures).
Xenopus
Tetraethylammonium is known as a pore-occluding blocker of voltage-gated potassium channels [ 1 ] , but it also blocks other cationic channels such as calcium-dependent K +channels [ 2 3 ] and the nicotinic acetylcholine receptor [ 4 ] . TEA at 0.1 to 10 mM also inhibits osmotic water flux through human AQP1 channels expressed in Xenopus oocytes, decreasing the net swelling rate in hypotonic saline by 30-40% as compared to AQP1-expressing oocytes not treated with TEA [ 5 ] . This blocking effect on osmotic water flux was demonstrated to involve AQP1 channels specifically by using site-directed mutagenesis (tyrosine 186 to phenylalanine) to generate a Y186F AQP1 channel that is insensitive to block by TEA, but retains sensitivity to block by mercury.
Proteasome activity is required for germinal vesicle breakdown (GVBD) in starfish and toad oocytes [ 44 45 ] and for activating Xenopus oocytes [ 45 46 ] . Also, proteasomes are needed for regulating centrosome segregation [ 38 47 ] , kinetochore structure [ 39 ] , and sister chromatid cohesion and separation [ 48 ] . When rat oocytes were exposed to the proteasome inhibitor MG132, proteasomes translocated to the meiotic spindle, MPF activity was sustained, and oocytes were arrested in MI with partially segregated chromosomes [ 42 ] .
For example, the Torpedo acetylcholine receptor and the Shaker K +channel protein differ in the fractions of protein glycosylated, the composition of the oligosaccharide chains, and the degree of protein maturation when expressed in Xenopus oocytes as compared with channels in native tissue or other expression systems [ 7 8 ] . Differences in glycosylation patterns can influence the binding of external blocking agents.
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