Words similar to word-pair
Example sentences for: word-pair
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For a certain experimental condition, the list of features was restricted to either two words found in a single word-pair template, or to all words found in conserved word-pair templates that were significantly associated with gene-expression changes in that condition.
The proportion of conserved word-pair templates showing significant associations with gene expression was compared to two sets of negative controls, comprising word pairs that failed either the first (co-conservation) or second (close spacing) statistical test.
Some groups of genes with shared word-pair templates were enriched for known targets of transcription factors.
Conserved word-pair templates accounted for similar changes in genome-wide expression ( R -square from approximately 11% to approximately 20%) using only 8 to 10 features, compared with dozens of overlapping features used by other methods [ 20 21 ] . Therefore, individual features from our methods were more predictive of genome-wide expression changes.
Over a third of the conserved word-pair templates were associated with gene-expression changes in multiple environmental stress conditions (Figure 4a, Tables 1, 2).
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