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Example sentences for: word-pair
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Two other statistical tests were also performed to examine how information contained in conserved word-pair templates compared to other sequence features derived from S. cerevisiae , or from single conserved words.
The underlying data for Figure 4that show associations between gene groups that share a conserved word-pair template with gene-expression changes
A tab-delimited text list of 989 identified conserved word-pair templates
The proportion of conserved word-pair templates showing significant associations with gene expression was compared to two sets of negative controls, comprising word pairs that failed either the first (co-conservation) or second (close spacing) statistical test.
We expect that if a sequence feature represented a transcription factor binding site, genes containing that feature in their TCRs would be induced (or repressed), on average, compared to all the genes in the genome [ 27 ] . By comparing the average expression profile derived from conserved word-pair templates with average expression profiles derived from simpler sequence features, we assessed how much information was obtained by incorporating both the conservation and pairwise combination of sequences.
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