Words similar to wnts
Example sentences for: wnts
How can you use “wnts” in a sentence? Here are some example sentences to help you improve your vocabulary:
In addition, LRP6 has been reported to bind Wnt-1 and to associate with Fz in a Wnt-dependent manner [ 8 ] . Taken together, these results support a co-receptor model: upon exposure to Wnts, LRP5 or LRP6 forms a complex with Wnt and Fzs, transducing the Wnt signal downstream to stabilize cytoplasmic β-catenin.
The mitogenic role played by Wnts in normal CNS development also supports the concept that the pathway could promote growth in the brain [ 21 22 ] . In order to test this hypothesis we created transgenic mice in which the Wnt pathway was aberrantly activated in the CNS.
Wnt proteins have been shown to bind to Frizzleds (Fzs), which are seven-transmembrane receptors [ 5 6 ] . The binding of Wnts occurs within an aminoterminal cysteine-rich-domain (CRD) of Fzs.
Whether they are direct or indirect does not alter the observation that the expression of both change in an unexpected manner in response to these two Wnts.
To our knowledge this is the first report to show that two genes are differentially regulated by two different Wnts within the same cell type.