Example sentences for: wis

How can you use “wis” in a sentence? Here are some example sentences to help you improve your vocabulary:

  • Genetically, the T Wis allele acts as a dominant negative in that T Wis / T Wis embryos have a more severe phenotype than the null T/T embryos.

  • In later whole mount in situ analysis, Herrmann [ 13 ] confirmed expression of a T locus-derived transcript in T Wis / T Wis embryos, but did not examine its exact nature.

  • Sequence analysis showed that this larger T Wis / T Wis specific band represented two additional aberrant transcripts (Table 2and Figure 3C).

  • Sequence analysis of the ~1300 bp PCR product amplified from T Wis / T Wis DNA in two independent reactions showed that the ETn element of the T Wis allele is identical to the 5542 bp ETn sequence, Genbank accession #Y17106, with the T Wis ETn element inserted in reverse orientation relative to the direction of transcription of the T locus (data not shown).

  • They showed that the splice site at the 3' end of exon 7 was mutated from TAG GTATGT to TAG GTGTTG (where underlined sequence is the 3' end of exon 7 and ETn insertion sequence is in bold) and predicted that this site would be nonfunctional, thereby abolishing splicing of exon 7 to exon 8. They proposed that the T Wis allele would produce a transcript comprised of exons 1 through 7 followed by read-through transcription of the ETn element, resulting in a modified C-terminal end, or alternatively, that upstream splice donor sites would be used, shortening the transcript and protein product.


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