Words similar to wildtype

Example sentences for: wildtype

How can you use “wildtype” in a sentence? Here are some example sentences to help you improve your vocabulary:

Polyubiquitylation of wildtype, but not mutant p27 was observed in untreated LNCaP cell lysate (Fig.
56 ± 0.14 fold) (Table 1) as compared to the wildtype receptor.
The Y140A mutation, however, produced a 50 fold increase in the K i compared to wildtype receptors (Figure 4C).
One of the hallmarks of cancer includes the accumulation of mutations in key genes, namely DNA repair genes [ 4 ] , tumor suppressor genes [ 5 6 ] , and proto-oncogenes [ 5 6 ] , accompanied by the loss of the wildtype allele, resulting in loss of heterozygosity [LOH, see reviews by [ 7 8 9 ] ]. Pancreatic cancer, which results in the death of approximately 30,000 Americans annually and is the fourth leading cause of cancer mortalities in the United States, exhibits this hallmark [ 10 ] . For example, in pancreatic cancer there is a high incidence of mutations (>50%) in the tumor suppressor genes p16, p53 and DPC4 and approximately 90% of cases coincide with a mutation in the oncogene K- ras 2 [see review by [ 11 ] ]. Furthermore, a significant percentage of tumors harboring a mutated copy of DPC4 or p53 also lose the corresponding wildtype allele, resulting in LOH [see reviews by [ 11 12 ] ].
This result is indicative of a weaker interaction between LcrG S23R and LcrV than the interaction between wildtype LcrG and LcrV.