Example sentences for: well-studied

How can you use “well-studied” in a sentence? Here are some example sentences to help you improve your vocabulary:

  • To determine whether flavopiridol affects transcription globally, we compared the gene expression profile of flavopiridol treatment with the gene expression profiles induced in OCI-Ly3 cells by treatment with two well-studied transcriptional inhibitors, actinomycin D and DRB.

  • Integrins are known to activate signaling pathways in cells [ 32 33 34 35 ] . Among the most well-studied signaling pathways is the Ras/MAPK pathway leading to activation of ERK1 and ERK2 [ 36 ] . We therefore decided to test the effect of cell adhesion to III1-C on ERK activation.

  • A well-studied megabase-scale region of DNA on distal mouse chromosome 7 (Chr7) contains multiple genes subject to parental imprinting.

  • The goals of this work were twofold: to use cDNA microarrays to characterize the primary response of intestinal epithelial cells to a well-studied intracellular pathogen, L. monocytogenes , and to try to identify host gene-expression programs which are induced by specific stages of the infection by comparing the wild-type expression profile to that of mutants which are either incapable of intracellular growth and thus avirulent, or which cannot initiate actin polymerization in host cell cytoplasm.

  • Their close homologs are, however, also found in Pseudomonas, but not in other well-studied proteobacterial lineages.


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