Words similar to well-established

Example sentences for: well-established

How can you use “well-established” in a sentence? Here are some example sentences to help you improve your vocabulary:

In the present study we set out to learn about the biological function of Rab24 by using a well-established paradigm in which a dominant-negative Rab construct is expressed in cultured cells, anticipating that it will suppress the trafficking step(s) mediated by its endogenous counterpart.
Due to the limited resource of the fresh tumor samples, we turned to the cell culture system and used the well-established rhabdomyosarcoma cell lines.
It is not suggested that well-established, traditional names be changed, only that boring names be replaced by interesting ones.
This amplification can be performed for thousands of genes during a given production run using well-established procedures that include microtiter plates and multichannel pipetting techniques to afford efficient parallel processing of the samples.
However, the present data in a well-established preclinical model of breast cancer, employing a variety of highly effective chemopreventive regimens, suggest that this is not the case.