Words similar to well-established

Example sentences for: well-established

How can you use “well-established” in a sentence? Here are some example sentences to help you improve your vocabulary:

To study the molecular mechanisms underlying capillary morphogenesis in ECs, we used a well-established in vitro model of angiogenesis.
Guess-work on word origins is not and probably cannot be science, since the matter is not involved with well-established general theories.
In this analysis, we used two of these well-established models, the Regional Modeling System for Aerosols and Deposition (REMSAD) and the Comprehensive Air Quality Model with Extensions (CAMx), to develop a picture of future changes in air quality resulting from the implementation of the Clear Skies Act.
Whole-mount RNA in situ hybridization is a well-established approach for determining precise spatial gene-expression patterns [ 5, 6], and can be done in high-throughput fashion [ 7, 8].
In order to distinguish between these possibilities, we sought to employ cell culture assays with well-established parameters for chondrocyte differentiation and maturation.