Words similar to well-established
Example sentences for: well-established
How can you use “well-established” in a sentence? Here are some example sentences to help you improve your vocabulary:
Even if these findings are not confirmed after further study, one could still make a compelling argument that lipid-lowering therapy (barring contraindications) should be initiated early and universally in patients who present with an acute coronary syndrome: First, the long-term safety and effectiveness of statins for the secondary prevention of stable coronary disease is well-established [ 1 2 3 ] ; Second, as evidenced by MIRACL, these agents are safe when initiated at the time of hospitalization for an acute coronary syndrome; Third, the in-hospital initiation of lipid-lowering therapy appears to promote greater long-term utilization of these agents [ 18 19 20 21 ] . Finally, although lipid levels may be unreliable in the setting of an acute coronary syndrome (excepting total :HDL and LDL:HDL cholesterol ratios [ 22 ] ) the overwhelming majority of patients with coronary disease will ultimately require both pharmacologic and non-pharmacologic lipid-lowering interventions to attain recommended cholesterol targets [ 23 24 25 ] ; newer guidelines are even more stringent [ 26 ] . Furthermore, data from the recently presented Heart Protection Study suggest that clinical benefits may accrue independent of baseline cholesterol level [ 4 ] . Thus, to withhold lipid-lowering therapy from patients who present with an acute coronary syndrome would be to accept the status quo, and to date our efforts at cholesterol lowering in the secondary prevention setting have been dismal [ 27 28 ] .
But as I read the quoted extracts from the opinion, the court's reasoning was not at all based on a definition of the word never but on a well-established precedent holding that to void the policy the misrepresentation must be such that had the company known the truth it would not have issued the policy.
In the absence of a well-established judiciary or organized police force, law and order was enforced by vigilantes, and summary hanging was the usual sentence.
Since wage slavery is a well-established phenomenon, and getting better established by the day, a little nonreproduction bribery sounds pretty mainstream.
Whole-mount RNA in situ hybridization is a well-established approach for determining precise spatial gene-expression patterns [ 5, 6], and can be done in high-throughput fashion [ 7, 8].
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