Example sentences for: well-characterized

How can you use “well-characterized” in a sentence? Here are some example sentences to help you improve your vocabulary:

  • However, the fact that SU5416 is an inhibitor of VEGF-mediated angiogenesis may be of relevance to the expression of MMP-9 mRNA, as the gene encodes a well-characterized enzyme with roles in angiogenesis and tissue remodeling.

  • Recently, the clinical features and human leukocyte antigen (HLA) associations of a well-characterized cohort of patients with synovitis of recent onset were presented [ 26].

  • MoeB, the molybdopterin synthase activating enzyme (MSAE), is part of the well-characterized molybdopterin cofactor (MPT-Mo) synthesis pathway.

  • It is present as a mid-level repeated element in its host insect genome (about 50 copies/genome) [ 19, 24], it encodes a set of proteins (gag, pol, env) with features similar to those of well-characterized retrovirus proteins [ 17] and it is capable of producing virus-like particles [ 25].

  • In contrast, insulin signal transduction pathways are well-characterized in a wide variety of cell types [ 8 10 ] . Insulin is known to primarily transduce its cellular actions via two signaling pathways, the p44/42 MAPK pathway and the PI 3-kinase pathway [ 8 10 ] . In the present study, we investigated the signaling pathways that mediate the inhibitory effects of insulin on the expression of the SP-A genes in human lung epithelial cells.


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