Words similar to well-characterized
Example sentences for: well-characterized
How can you use “well-characterized” in a sentence? Here are some example sentences to help you improve your vocabulary:
However, neither direct comparisons, nor sequence-structure threading revealed any relationship with the two other well-characterized α-helical heme-binding domains, namely globin and cytochrome C. Hence, it is likely that the HNOB domain adopts a structure distinct from these domains.
Here, we ask whether infected podocytes expressing HIV-1 genes show the hallmarks of cyclin D 1 -dependent proliferation, specifically the up-regulation of cyclin D 1 transcript and protein expression and the subsequent phosphorylation of pRb on serine 780, a target site of active cyclin D 1 /CDK-4/6 that is not shared with cyclin E/CDK-2 complexes [ 24 ] . Utilizing two well-characterized models of HIVAN pathogenesis, HIV-1 transgenic mice [ 11 12 13 ] and HIV-1 infection of cultured podocytes [ 6 7 8 ] we find not only these hallmarks of cyclin D 1 -dependent proliferation, but also dysregulation of cyclin D 1 expression that normally occurs with cell-cell contact and differentiation [ 25 ] .
We demonstrate this approach by applying it to the well-characterized data of Spellman et al . [ 23].
One of the three main classes of cytoskeletal proteins, the intermediate-filament proteins, represents a well-characterized group of coiled-coil proteins.
Stat3 has been shown to enhance AR-mediated PSA expression and AR transcriptional activity in prostate cancer cells [ 16 25 28 ] . We used two well-characterized androgen-responsive luciferase reporter plasmids to study the effect of Stat3 on AR-mediated transcriptional activity.
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