Example sentences for: well-characterized

How can you use “well-characterized” in a sentence? Here are some example sentences to help you improve your vocabulary:

  • A URA3-marked tester mini-chromosome carrying the SUP11 suppressor transfer RNA gene [ 34 ] ) was introduced into net1 tab 2-1and CDC14 TAB 6-1, the two tab mutants with well-characterized bypass mechanisms.

  • In addition, the logistical problem of obtaining DNA samples from clinically well-characterized members of a cohort of stroke pedigrees can be a daunting task.

  • Nevertheless, DNA microarrays have been successfully applied in the analysis of aging and caloric restriction [ 13 ] and pulmonary fibrosis [ 14 ] . And many publications, particularly on cancer, have appeared [ 14 15 16 17 18 19 ] . Affymetrix has recently announced the availability of the U133 GeneChip series with 33,000 well-characterized human genes mined from genomic sequence.

  • Stat3 has been shown to enhance AR-mediated PSA expression and AR transcriptional activity in prostate cancer cells [ 16 25 28 ] . We used two well-characterized androgen-responsive luciferase reporter plasmids to study the effect of Stat3 on AR-mediated transcriptional activity.

  • However, neither direct comparisons, nor sequence-structure threading revealed any relationship with the two other well-characterized α-helical heme-binding domains, namely globin and cytochrome C. Hence, it is likely that the HNOB domain adopts a structure distinct from these domains.


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