Words similar to well-characterized

Example sentences for: well-characterized

How can you use “well-characterized” in a sentence? Here are some example sentences to help you improve your vocabulary:

One of the three main classes of cytoskeletal proteins, the intermediate-filament proteins, represents a well-characterized group of coiled-coil proteins.
The genus Drosophila offers a well-characterized evolutionary genetic system for developing and testing methods for comparative genome annotation.
MoeB, the molybdopterin synthase activating enzyme (MSAE), is part of the well-characterized molybdopterin cofactor (MPT-Mo) synthesis pathway.
Here, we ask whether infected podocytes expressing HIV-1 genes show the hallmarks of cyclin D 1 -dependent proliferation, specifically the up-regulation of cyclin D 1 transcript and protein expression and the subsequent phosphorylation of pRb on serine 780, a target site of active cyclin D 1 /CDK-4/6 that is not shared with cyclin E/CDK-2 complexes [ 24 ] . Utilizing two well-characterized models of HIVAN pathogenesis, HIV-1 transgenic mice [ 11 12 13 ] and HIV-1 infection of cultured podocytes [ 6 7 8 ] we find not only these hallmarks of cyclin D 1 -dependent proliferation, but also dysregulation of cyclin D 1 expression that normally occurs with cell-cell contact and differentiation [ 25 ] .
Irrespective of the upstream mechanism of FFA and CD36 interaction, our results demonstrate very rapid activation of a well-characterized intracellular kinase cascade of proapoptotic signaling.