Example sentences for: wd

How can you use “wd” in a sentence? Here are some example sentences to help you improve your vocabulary:

  • WD participated in the design of the study.

  • WD, LW, PQ carried out the data analysis and drafted the manuscript.

  • Phosphorylated Sic1, but not the unmodified protein, is recruited to the SCF complex by binding to the WD domain of Cdc4 [ 5 ] [ 6 ] . The F-box motif of Cdc4 binds Skp1 so that the F-box protein acts as a bridge between substrate and the SCF complex.

  • Although we have no direct biochemical evidence to confirm this proposition, which would require Pop2p point mutants deficient in Pop1p binding, our data show that severely truncated N-terminal fragments of Pop1p and Pop2p lacking both F-boxes and WD repeat domains are sufficient to mediate their interaction (Fig.

  • A number of RING finger proteins have recently been shown to act as E3 ubiquitin ligases [ 24 ] . WD40 domains have also been frequently found in E3 complexes as substrate recruiting domains [ 25 26 27 28 ] . Despite compelling evidence from Arabidopsis implying that COP1 may mediate protein degradation [ 4 5 ] , no direct evidence of COP1 participating in ubiquitination has been reported.


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