Example sentences for: venules

How can you use “venules” in a sentence? Here are some example sentences to help you improve your vocabulary:

  • One of the first parallel plate flow chamber described to study neutrophil adhesion to endothelium was described in 1987 by Lawrence et al [ 7 ] . Initially, several investigators produced chambers identical to or very similar to this design, and over the years this initial design has been the most widely used [ 8 ] . This design allowed for study of leukocyte-endothelial interaction from a top-down view and under laminar flow that occurs in the post-capillary venules, the physiologically relevant site for most leukocyte emigration.

  • Furthermore, post-capillary venules, the physiologically relevant site of leukocyte extravasation, have diameters of 30-80 μm [ 19 ] . Finally, technical issues occurred with 0.01" ID (see below).

  • The one used most often (SH-2) was recently shown to react with endoglin (CD105), a member of the transforming growth factor (TGF)-β receptor family usually found on the endothelium of postcapillary venules [ 4].

  • HEV (high endothelial venules)

  • SLC/CCL21, normally expressed in high endothelial venules and in T cell zones of spleen and lymph nodes, strongly attracts T cells and dendritic cells (DC) [ 1 2 3 4 5 6 7 8 ] . SLC/CCL21 recruits both naïve lymphocytes and antigen stimulated DC into T cell zones of secondary lymphoid organs, co-localizing these early immune response constituents that culminate in cognate T cell activation [ 1 ] . The capacity to facilitate the co-localization of both DC and T cells forms a strong rationale for the use of SLC/CCL21 in cancer therapy.


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