Words similar to ventilatory
Example sentences for: ventilatory
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Maintenance of splanchnic blood flow is important because splanchnic hypoperfusion may play a critical role in the pathogenesis of multiorgan dysfunction syndrome [ 2 3 ] . Mechanical ventilation has been suggested to potentiate the adverse effects of underlying critical illness on splanchnic vasculature and contribute to the development of multiorgan dysfunction syndrome, particularly when 'injurious' ventilatory strategies that produce high end-inspiratory lung volumes are employed [ 3 ] . Experimental studies suggested that mechanical ventilation with considerably high levels of PEEP can lead to splanchnic hypoperfusion and marked reduction in hepatic blood flow [ 4 5 6 ] . Furthermore, PEEP may decrease splanchnic blood flow in patients with no underlying lung disease [ 7 8 ] . Most available evidence regarding the effects of PEEP from animal studies has been extrapolated to humans based on the assumption that the effects of mechanical ventilation on humans and animals are similar.
Prior studies have shown variability in the use of therapeutic modalities (including PACs, ventilator, and intravenous vasoactive and inotropic agents) among ICU patients [ 21 27 ] and different impacts on outcomes and use of hospital resources associated with these treatments [ 16 17 18 28 29 ] . In general, with the exception of the recent trial demonstrating benefit of early goal-directed treatment involving oxygenation (including ventilatory support if necessary) and blood pressure (including intravenous pressors if necessary) [ 30 ] , few data are available that demonstrate that these modalities improve outcomes.
Baseline measurements were made following a 1 h steady state of conventional mechanical ventilation using the following ventilatory settings: FiO 2 0.85, PEEP 10 cmH 2 O, inspiratory time 30%, respiratory frequency 16 ± 2 bpm, V T 728 ± 32 ml.
Primary diagnoses (based on ICD-9 diagnostic codes) of patients requiring ICU admission and ventilatory support are summarized in Table 2. The diagnostic categories included: respiratory, 75 (33%); cardiovascular, 72 (32%); digestive, 33 (15%); and other (20%).
Cardiac or respiratory arrest precipitated ventilatory care in only 5.8% of instances.
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