Example sentences for: vasoconstriction

How can you use “vasoconstriction” in a sentence? Here are some example sentences to help you improve your vocabulary:

  • Under more physiologically relevant levels of hypoxia, the central role of eNOS in protecting against hypertension is supported by our observation that loss of eNOS leads to increased acute hypoxic vasoconstriction and development of pulmonary hypertension [ 9, 10, 11, 12].

  • It is well known that acute lung infection and septic shock may impair hypoxic pulmonary vasoconstriction through the massive release from activated endothelium of vasodilating mediators such as prostaglandins and endogenous NO, and hence result in disproportionately high shunting and hypoxemia [ 26, 27, 28, 29, 30, 31, 32].

  • NO has been proposed as a modulator of vascular tone and structure in the pulmonary circulation, and previous studies using NOS inhibitors [ 1, 2] suggested that inhibition of NO increases acute hypoxic pulmonary vasoconstriction.

  • In addition, exogenous catecholamines, used to maintain arterial pressure during septic shock, interfere with hypoxic pulmonary vasoconstriction: vasodilators like isoproterenol or dobutamine tend to inhibit hypoxic pulmonary vasoconstriction whereas vasoconstrictors like dopamine, epinephrine or norepinephrine tend to reinforce hypoxic pulmonary vasoconstriction.

  • severity and/or duration of vasoconstriction, extraction ratio) to small changes in DO 2 among individuals.


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