Words similar to vasculature
Example sentences for: vasculature
How can you use “vasculature” in a sentence? Here are some example sentences to help you improve your vocabulary:
In this plant, McMIPB is highly expressed in the root vasculature although not in the primary meristem of the root [ 55].
In some circumstances, CD4 +and CD8 +T cells were rendered inactive in tumor-bearing hosts [ 8 ] . The inactivation of CD4 +T cells has been attributed either to the tumor cells themselves or to bone marrow-derived cells [ 9 10 11 ] , whereas antigen ignorance or loss of memory have been postulated to underlay that of CD8 +T cells [ 12 13 ] . Other studies have suggested that tumor cells can secrete immunosuppressive factors such as TGF-β or express Fas ligand to induce apoptosis of infiltrating lymphocytes [ 14 15 16 ] . Furthermore, the tumor vasculature appears to be quite different from normal blood vessels, in terms of structural organization, interstitial pressure, and flow patterns [ 17 ] , and in reduced lymphocyte and natural killer cell homing and adhesion [ 18 19 20 21 ] . The existence of significant barriers to effective immunological destruction is further illustrated by a mouse model of concurrent multistage tumorigenesis and anti-oncogene autoimmunity, wherein progenitor dysplastic lesions are infiltrated and disrupted, while solid tumors are not [ 22 ] . The hypothesis is that the microenvironment of certain types of solid tumor can serve to locally suppress T cell infiltration.
Maintenance of cardiac output during mechanical ventilation with high PEEP may be adequate to prevent its unwanted effects on organs in the splanchnic vasculature.
Indeed, a recent study on the nitrogen content of phloem and xylem exudates during the transition to flowering in Arabidopsis and Sinapis alba showed changes in the transport of amino acids through the vasculature [ 30 ] .
Maintenance of splanchnic blood flow is important because splanchnic hypoperfusion may play a critical role in the pathogenesis of multiorgan dysfunction syndrome [ 2 3 ] . Mechanical ventilation has been suggested to potentiate the adverse effects of underlying critical illness on splanchnic vasculature and contribute to the development of multiorgan dysfunction syndrome, particularly when 'injurious' ventilatory strategies that produce high end-inspiratory lung volumes are employed [ 3 ] . Experimental studies suggested that mechanical ventilation with considerably high levels of PEEP can lead to splanchnic hypoperfusion and marked reduction in hepatic blood flow [ 4 5 6 ] . Furthermore, PEEP may decrease splanchnic blood flow in patients with no underlying lung disease [ 7 8 ] . Most available evidence regarding the effects of PEEP from animal studies has been extrapolated to humans based on the assumption that the effects of mechanical ventilation on humans and animals are similar.
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