Example sentences for: vasculature

How can you use “vasculature” in a sentence? Here are some example sentences to help you improve your vocabulary:

  • Maintenance of splanchnic blood flow is important because splanchnic hypoperfusion may play a critical role in the pathogenesis of multiorgan dysfunction syndrome [ 2 3 ] . Mechanical ventilation has been suggested to potentiate the adverse effects of underlying critical illness on splanchnic vasculature and contribute to the development of multiorgan dysfunction syndrome, particularly when 'injurious' ventilatory strategies that produce high end-inspiratory lung volumes are employed [ 3 ] . Experimental studies suggested that mechanical ventilation with considerably high levels of PEEP can lead to splanchnic hypoperfusion and marked reduction in hepatic blood flow [ 4 5 6 ] . Furthermore, PEEP may decrease splanchnic blood flow in patients with no underlying lung disease [ 7 8 ] . Most available evidence regarding the effects of PEEP from animal studies has been extrapolated to humans based on the assumption that the effects of mechanical ventilation on humans and animals are similar.

  • Because ARDS is associated with abnormalities of the pulmonary vasculature (local thrombi and pulmonary vasoconstriction at the early stage and vascular remodeling at the late stage), VD A /V T can be considered as a better index of these vascular lesions than physiologic dead space calculated by the Bohr equation which takes into account the anatomic dead space [ 19].

  • These findings indicate that prolonged neutrophil survival in the lung vasculature following endotoxin administration may be mediated, at least in part, by Mcl-1.

  • It has been previously shown that PGE2 not only directly dilates renal arteries [ 9 10 11 ] but also attenuates the AngII-induced increase in renal vascular resistance [ 12 ] through inhibition of AngII-elicited intracellular Ca ++increase in vascular smooth muscle cells of preglomerular vasculature [ 13 ] . Based on the fact that PGE2 stimulates cAMP generation in freshly isolated preglomerular renal arterioles [ 14 ] , the cAMP-stimulating EP2 or EP4 receptor has been thought to mediate these effects of PGE2 on renal resistance vessels.

  • DCGs are lignan-glucosides with cytokinin-like activity [ 28 29 ] . An alternative hypothesis is that as a result of the bmr mutations the physico-chemical characteristics of the vasculature have been altered in such a way that it affects the transport of signaling compounds.


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