Words similar to vacuolation
Example sentences for: vacuolation
How can you use “vacuolation” in a sentence? Here are some example sentences to help you improve your vocabulary:
Our results as well as others' show that mitochondrial vacuolation provides an important window for examination of the mechanism whereby mutant SOD1 causes mitochondrial damage and motor neuron degeneration.
Taken together, this study reveals a mitochondrial degeneration mechanism in the CNS, mitochondrial vacuolation by intermembrane space expansion or MVISE.
These observations indicate that neither MPT (expansion of matrix) nor autophagy (in which lysosomes participate) is responsible for mutant SOD1-induced mitochondrial vacuolation.
The increased cell death induced by direct targeting of mutant SOD1 to mitochondria supports this possibility [ 27 ] . Interestingly, low levels (compared with the levels caused by mutant SOD1) of mitochondrial vacuolation can also be caused by expression of high levels of wild type SOD1 [ 7 13 15 41 ] , suggesting that the mitochondria-damaging property also exists in the wild type protein and this property strengthens by the mutations.
The absence of matrix expansion and the involvement of peroxisomes but not lysosomes together indicate that mutant SOD1-induced mitochondrial vacuolation is neither MPT nor autophagy.