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Approximately 8500 16S and 16S-like rRNA sequences and 1050 23S and 23S-like rRNA sequences were collected from all branches of the phylogenetic tree, as shown in Section 2, "Nucleotide Frequency and Conservation Information" and in Table 2. These sequences have been aligned and analyzed with several covariation algorithms, as described in more detail in the "Predicting RNA Structure with Comparative Methods" section of the CRW Site http://www.rna.icmb.utexas.edu/METHODS/and in Section 2A.
This collection of RNA structure models was predicted with covariation analysis, as described at the CRW Site Methods Section http://www.rna.icmb.utexas.edu/METHODS/and in several publications (see below).
The RNA structure models presented here are composed of several different basic building blocks (or motifs) that are described and illustrated at our RNA Structure Definitions page http://www.rna.icmb.utexas.edu/CSI/DEFS/(H-1C.
Some highlights from these detailed tables are captured in summary tables (Tables 3aand 3b, and http://www.rna.icmb.utexas.edu/CSI/EVOLUTION/) that compare the numbers of sequences and base pairs predicted correctly and incorrectly for each of the major versions of the 16S and 23S rRNA structure models.
The number of different tRNA secondary structure models is approximately 2.5 × 10 19; there are approximately 10 393and 10 740possible structure models for 16S and 23S rRNA, respectively (see CRW Methods http://www.rna.icmb.utexas.edu/METHODS/).