Example sentences for: upon

How can you use “upon” in a sentence? Here are some example sentences to help you improve your vocabulary:

  • It shouldn't have been a complete surprise when I walked into the elevator in my Washington office building and came upon Dick Morris clutching a book by the late Cardinal Bernardin.

  • He did nothing about scandals at the FSB (the successor agency to the KGB) when he was its director, and "[a]s prime minister, his only claim to fame has been to seize upon a truly bad situation in Chechnya as an excuse to wage an imperial war, one that punishes civilians in the name of protecting them."

  • Drawing upon her rich experience of life, Prudence (Prudie to her friends) responds to questions about manners, personal relations, politics, and other subjects.

  • Sphingomyelin content and luteal cell membrane fluidity decrease during luteolysis in vivo [ 48 49 50 51 ] . Ceramide, a product of sphingomyelin hydrolysis, is a potent stress-activated second messenger and is well established as a functional component of death receptor-mediated apoptosis [ 52 53 54 ] . Upon treatment of CLENDO cells with TNFα, we observed a rapid and sustained increase in the production of ceramide, suggesting that the sphingomyelin pathway is present and active in these cells.

  • Although myofibroblasts were not detected in vivo [ 51 ] , the propensity of keloid fibroblasts to express α-SMA in vitro and the loss of this protein upon matrix contraction (gel relaxation) do not allow one to dismiss a role for myofibroblasts in keloids.


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