Example sentences for: up-

How can you use “up-” in a sentence? Here are some example sentences to help you improve your vocabulary:

  • These genes were assigned into functional classes and characterized as up- and down-regulated.

  • The third assumption is important for signal-dependent normalizations and is supported by the intuition that genes with 100 to 1,000 mRNA copies per cell will be no more or less biased toward up- or downregulation than genes with 10,000 to 100,000 copies per cell.

  • Since different dilutions, different cycles of PCR and dye reverse were used, ADGE magnification can be applied for up- and down-regulated genes with different abundance.

  • 3D); 107 and 38 genes detected at >4 fold up- and down-regulated, respectively.

  • In hamsters, rats and mice, increases and decreases in bile acid absorption at the brush border membrane are mediated by an up- or down-regulation in IBAT gene transcription [ 33 34 ] . In several rodent species including mice, regulation of IBAT is clearly dependent on intraluminal bile acid concentrations and occurs via a negative feedback mechanism [ 33 34 35 ] . Feeding of bile acids suppresses transcription of IBAT mRNA and reduces IBAT protein abundance; feeding of the bile acid binder cholestyramine has the opposite effect.


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