Words similar to up-
Example sentences for: up-
How can you use “up-” in a sentence? Here are some example sentences to help you improve your vocabulary:
Anderson's museum is traditional, art-history-minded, and eager to ingratiate itself with, rather than flabbergast and dumbfound, up- and out-of-towners.
For each pair of experimental conditions, a gene was considered to be "regulated" if it showed at least a two-fold change in expression level (either up- or down-regulated) between conditions, and "unregulated" if the expression ratio was less than two-fold.
Spearman's rank order correlation determined significant monotonic relationships that illuminate important connections between structural features in tissue elements and genes that have been reported as significantly up- or downregulated by CCl 4 treatment in previous studies [ 7 ] . Principal component analysis (PCA), as described in Materials and methods, was carried out to reduce the complexity of the data [ 15 ] and then to relate individual animals to specific phenotypic groups.
In hamsters, rats and mice, increases and decreases in bile acid absorption at the brush border membrane are mediated by an up- or down-regulation in IBAT gene transcription [ 33 34 ] . In several rodent species including mice, regulation of IBAT is clearly dependent on intraluminal bile acid concentrations and occurs via a negative feedback mechanism [ 33 34 35 ] . Feeding of bile acids suppresses transcription of IBAT mRNA and reduces IBAT protein abundance; feeding of the bile acid binder cholestyramine has the opposite effect.
A cutoff of twofold up- or down-regulation has been chosen to define differential expression in most published studies [ 1, 2].
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