Example sentences for: up-

How can you use “up-” in a sentence? Here are some example sentences to help you improve your vocabulary:

  • Spearman's rank order correlation determined significant monotonic relationships that illuminate important connections between structural features in tissue elements and genes that have been reported as significantly up- or downregulated by CCl 4 treatment in previous studies [ 7 ] . Principal component analysis (PCA), as described in Materials and methods, was carried out to reduce the complexity of the data [ 15 ] and then to relate individual animals to specific phenotypic groups.

  • The p53 protein is known to function as a transcriptional regulator by either up- or down regulating target genes in response to different forms of cellular stress, including irradiation-induced DNA damage.

  • Anderson's museum is traditional, art-history-minded, and eager to ingratiate itself with, rather than flabbergast and dumbfound, up- and out-of-towners.

  • For each pair of experimental conditions, a gene was considered to be "regulated" if it showed at least a two-fold change in expression level (either up- or down-regulated) between conditions, and "unregulated" if the expression ratio was less than two-fold.

  • Genes were chosen for further study by being up- or down-regulated by at least 2.5-fold compared to controls in at least one of the four probe pairs.


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