Example sentences for: up-

How can you use “up-” in a sentence? Here are some example sentences to help you improve your vocabulary:

  • In hamsters, rats and mice, increases and decreases in bile acid absorption at the brush border membrane are mediated by an up- or down-regulation in IBAT gene transcription [ 33 34 ] . In several rodent species including mice, regulation of IBAT is clearly dependent on intraluminal bile acid concentrations and occurs via a negative feedback mechanism [ 33 34 35 ] . Feeding of bile acids suppresses transcription of IBAT mRNA and reduces IBAT protein abundance; feeding of the bile acid binder cholestyramine has the opposite effect.

  • Anderson's museum is traditional, art-history-minded, and eager to ingratiate itself with, rather than flabbergast and dumbfound, up- and out-of-towners.

  • Spearman's rank order correlation determined significant monotonic relationships that illuminate important connections between structural features in tissue elements and genes that have been reported as significantly up- or downregulated by CCl 4 treatment in previous studies [ 7 ] . Principal component analysis (PCA), as described in Materials and methods, was carried out to reduce the complexity of the data [ 15 ] and then to relate individual animals to specific phenotypic groups.

  • The third assumption is important for signal-dependent normalizations and is supported by the intuition that genes with 100 to 1,000 mRNA copies per cell will be no more or less biased toward up- or downregulation than genes with 10,000 to 100,000 copies per cell.

  • It has a very dramatic expression profile in which hundreds of genes are rapidly (within minutes) up- or down-regulated.


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