Example sentences for: unwinding

How can you use “unwinding” in a sentence? Here are some example sentences to help you improve your vocabulary:

  • Assays for DNA-dependent ATPase and oligonucleotide unwinding were performed as before [ 10].

  • Regulation of DNA-dependent processes such as transcription, replication, and strand repair requires bending and unwinding of compacted chromatin structure.

  • The interaction of DnaA with DnaA boxes promotes the local unwinding of a nearby AT-rich region, providing an entry site for the DnaB/DnaC helicase complex.

  • RAR/RXR binding to nuclear receptor corepressors such as NCoR and SMRT in the absence of ligand inhibits activation of RA responsive genes [ 3 4 ] . Ligand binding displaces the repressors and recruits coactivator proteins such as CBP which have histone acetyltransferase activity [ 5 ] . Histone acetylation allows for chromatin unwinding and transcriptional initiation of target gene expression [ 6 ] .

  • An AT-rich stretch of 19 nucleotides (74% A+T), which in other bacteria serves as the site of local unwinding of DNA after DnaA-DNA interaction, was located in non-coding sequence adjacent to dnaA (Fig.


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