Words similar to unsaturated
Example sentences for: unsaturated
How can you use “unsaturated” in a sentence? Here are some example sentences to help you improve your vocabulary:
It has been proposed that vitamin E may incorporate into cellular membranes by association of the tocopherol side chain with the polyenoic fatty acid residues in the membrane fatty acids [ 15 19 ] . This interaction may stabilize cell membranes by making highly unsaturated fatty acids less liable to peroxidation as well as by making highly unsaturated fatty acids less available for phospholipid hydrolysis by phospholipase [ 15 16 ] . The latter action may reduce mobilization of arachidonic acid (AA) from the membranes and in this way reduce the amount of AA available as a substrate to cyclooxygenase and/or lipoxygenase to produce eicosanoids with mitogenic and with inflammatory properties [ 17 20 ] . Other possible antitumor actions include: induction of apoptosis, interference with hormone production, modulation of cellular signaling and gene transcription, and induction of differentiation [ 4 21 22 23 24 ] .
These domains, and the associated properties such as activation by unsaturated fatty acids are by far the most noteworthy features of PfPP5.
These results are reminiscent of similar studies done in other PP5 enzymes in which mutational inactivation of the TPR domain resulted in an elevated basal activity and concomitant reduced response to unsaturated fatty acids [ 19 ] . Such studies led to the proposal that TPR domains regulate the PP5 catalytic region in a negative manner and that the interaction of arachidonic acid with TPR relieves this auto-inhibition.
This is especially true for the unsaturated fatty acid content of brine shrimp nauplii, Artemia.
Peroxisomes shorten chains of very long fatty acids, unsaturated fatty acids and branched fatty acids by β-oxidation [ 60 61 ] . They play critical roles in synthesis of ether phospholipids and cholesterol [ 62 63 ] . Peroxisomal abundance is associated with high membrane demand such as myelination in the central nervous system [ 64 65 ] and peroxisome diseases result in defective myelination [ 66 ] . Because the outer mitochondrial membrane normally tightly wraps around mitochondria, the extension of the outer membrane during vacuolation requires new membranes.
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