Words similar to unphosphorylated
Example sentences for: unphosphorylated
How can you use “unphosphorylated” in a sentence? Here are some example sentences to help you improve your vocabulary:
These attributes are reminiscent of the behavior of MHCK-A, which upon purification exists in an unphosphorylated low activity state.
Unphosphorylated p53-GST was not a substrate for GSK3β, whereas p53-GST prephosphorylated by DNA-PK was (fig 2).
Triggering of the UPR also results in the suppression of global protein synthesis, as PERK is activated and phosphorylates EIK2α, which can only interact with the appropriate ribosomal binding sites in an unphosphorylated state [ 11 12 ] . While the upregulated transcription of PERK is not required for its activation, it's over expression can lead to the enhanced phosphorylation (and therefore inactivity) of EIK2α [ 16 ] . Therefore, its up-regulation by mefloquine supports the hypothesis that the drug triggers an UPR.
Investigators have shown that v-crk interacts via its SH2 domain with the substrate domain of Cas [ 6 ] . Association of v-crk with endogenous Cas is believed to protect the phosphorylation status of this molecule due to protection from phosphatases [ 12 ] . Expression of an unphosphorylated Cas SD along with v-crk should therefore result in stable tyrosine phosphorylation of the Cas SD if they interact.
The Ab is specific for the phosphorylated form of STAT3; it does not bind to unphosphorylated STAT3 or to other phosphorylated signaling intermediates.