Words similar to unphosphorylated

Example sentences for: unphosphorylated

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Triggering of the UPR also results in the suppression of global protein synthesis, as PERK is activated and phosphorylates EIK2α, which can only interact with the appropriate ribosomal binding sites in an unphosphorylated state [ 11 12 ] . While the upregulated transcription of PERK is not required for its activation, it's over expression can lead to the enhanced phosphorylation (and therefore inactivity) of EIK2α [ 16 ] . Therefore, its up-regulation by mefloquine supports the hypothesis that the drug triggers an UPR.
The Ab is specific for the phosphorylated form of STAT3; it does not bind to unphosphorylated STAT3 or to other phosphorylated signaling intermediates.
Investigators have shown that v-crk interacts via its SH2 domain with the substrate domain of Cas [ 6 ] . Association of v-crk with endogenous Cas is believed to protect the phosphorylation status of this molecule due to protection from phosphatases [ 12 ] . Expression of an unphosphorylated Cas SD along with v-crk should therefore result in stable tyrosine phosphorylation of the Cas SD if they interact.
Possibly, this assembly reflects interactions between CycT1 and the unphosphorylated CTD of RNAPIIa [15].
Substitution of the three threonines with alanines produces the 3 × Ala mutant that behaves like a constitutively unphosphorylated myosin-II.